the difference between phthalaldehyde and glutaraldehyde

For high-level disinfection of soft endoscopes, phthalaldehyde, glutaraldehyde, peroxyacetic acid, chlorine dioxide, acidic chlorinated potential water, etc. can be used; for sterilization of soft endoscopes, sterilization equipment or peroxyacetic acid or pentane can be used Dialdehyde and so on.

　　O-phthalaldehyde and glutaraldehyde are both high-level disinfectants, but there is a big difference between the two:

1. High-level disinfection time: Glutaraldehyde takes 20 minutes, and phthalaldehyde only takes 5 minutes;

2. Toxicity: Glutaraldehyde belongs to low toxicity grade, phthalaldehyde is actually non-toxic grade;

3. Corrosion: Glutaraldehyde is corrosive, while phthalaldehyde is basically non-corrosive;

4. Toxic and side effects: glutaraldehyde is easy to cause teratogenic, mutagenic and carcinogenic effects, while phthalaldehyde has basically no side effects;

5. Concentration and anti-interference: 2% glutaraldehyde, interfered by organic matter; phthalaldehyde 0.55%, anti-interference of organic matter;

6. Drug resistance: glutaraldehyde tuberculosis and mycobacteria are resistant, while phthalaldehyde is not resistant;

7. Irritation: Glutaraldehyde irritates the skin and respiratory tract mucosa, no significant irritation of o-phthalaldehyde;

8. Sewage treatment requirements: Discharge after glutaraldehyde treatment, direct discharge of phthalaldehyde;

9. Product shelf life: glutaraldehyde 6-12 months, phthalaldehyde 24 months;

10. Endoscopic daily turnover rate (8 hours): 16 times glutaraldehyde and 24 times phthalaldehyde;

11. The longest use time: Glutaraldehyde and phthalaldehyde are both 14 days.

　　Advantages of phthalaldehyde:

1. Faster: ready to use, no need to activate, mix or dilute; achieve high-level disinfection in 5 minutes; save 50%-75% of time than glutaraldehyde; shorten the endoscope disinfection cycle and increase the turnover rate;

2. More efficient: broad-spectrum bactericidal effect; kill 2% glutaraldehyde-resistant mycobacteria, especially Mycobacterium chelonae strain in 5 minutes;

3. Safer: no special ventilation device required; no OSHA allowable explosion limit requirements; no inhalation toxicity, mucosal toxicity; no acute toxicity, teratogenicity, mutagenicity reported so far in the past ten years of widespread use;

4. More lasting: under high load, the average sustainable disinfection cycle> glutaraldehyde (glutaraldehyde is about 40 cycles);

5. Material compatibility: PH value is stable, close to neutral, more gentle; wide material compatibility;

6. Application department and scope:

a. Endoscope disinfection room and operating room: Endoscope disinfection (gastroscopy, enteroscopy, bronchoscopy, laryngoscope, colposcopy)

b. Disinfection of speculum, dental equipment, etc. in the medical office/dental office

c. Disinfection of pipes, resuscitators and sprayers for respiratory therapy

d. Hospital Disinfection Supply Center

Application benefits of o-phthalaldehyde

1. Reduce occupational injuries to medical staff in the areas of skin, respiratory mucosa, reproductive system, nervous system, etc.

2. Reduce environmental pollution, especially hospital sewage system and air

3. Overcome the drug resistance of Mycobacterium tuberculosis and Mycobacterium, ensure the quality of medical treatment, avoid the occurrence of cross-infection, and reduce the economic and reputational losses caused by medical disputes to the hospital

4. Shorten the endoscope disinfection time, increase the endoscope use turnover rate, and bring considerable economic benefits to departments and hospitals