Profenofos (CAS 41198-08-7): Sourcing Guide for Agricultural Chemical Buyers

Profenofos

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Profenofos (CAS 41198-08-7) is an organophosphorus insecticide and acaricide used primarily in agricultural applications for the control of cotton pests, spider mites, and a range of sucking and chewing insects on field crops. The active ingredient belongs to the phosphorothioate class of organophosphates, with a chemical structure featuring a bromine and chlorine substituent on the aromatic ring that distinguishes it from closely related compounds like chlorpyrifos.
 
Buyers approaching Profenofos from the procurement side are typically either technical-grade ingredient buyers for formulation, or traders managing supply for national registration holders. The quality expectations and documentation requirements for these two groups are meaningfully different.

Purity Specification and Formulation-Grade Criteria

 
Technical-grade Profenofos for formulation is typically specified at 90% minimum active ingredient content or higher, with specific limits on sulfoxide analog and other organophosphate-related impurities. The sulfoxide impurity is the primary concern — it forms during storage if the product is exposed to moisture or oxidizing conditions, and it affects both the biological efficacy and the regulatory residue profile.
 
When reviewing a CoA for technical Profenofos, confirm that impurity testing covers the sulfoxide and degradation products specifically, not just a total purity by GC. The two measurements are different and the second one is the one that matters for formulation registration compliance.

Physical and Chemical Properties Relevant to Handling

Profenofos is a pale yellow to amber liquid at ambient temperature, with a boiling point of approximately 100°C at 0.001 mmHg and a specific gravity near 1.455 at 20°C. It is miscible with most common organic solvents and practically insoluble in water. The density is higher than water, which matters for packaging calculations and spill response planning.
 
Like all organophosphorus compounds, Profenofos is an acetylcholinesterase inhibitor. Handling requires appropriate PPE: nitrile or neoprene gloves, chemical splash goggles, and adequate ventilation. Do not handle near food or animal feed. Review the SDS for full exposure guidelines before your first receipt.

Regulatory Status and Import Considerations

Profenofos is registered for agricultural use in many countries but is restricted or under review in others, including certain EU member states that have not renewed registration under EC 1107/2009. Before importing, verify the registration status in your destination country. If Profenofos is not currently registered in your market, you may need to engage with the national regulatory body about the import pathway — this is separate from customs clearance and takes longer.
 
For countries where Profenofos is registered, import documentation typically requires the batch COA, GHS-compliant SDS, origin documentation, and in some cases the batch production record for traceability back to the manufacturing facility. sdlookchem can provide all of these documents on request.
Profenofos

Storage and Shelf Life

⇒Technical Profenofos should be stored in sealed, chemically resistant containers away from heat and direct sunlight. Under proper storage conditions (below 25°C, dry, away from light), shelf life is typically two years from the production date. Confirm the production date on each batch CoA and factor this into your inventory planning — buying 12 months’ supply when your registered formulation requires within-specification material throughout the year is a common inventory miscalculation for seasonal active ingredients.
 

sdlookchem Supply of Profenofos 

Shandong Lookchemical Co., Ltd. manufactures Profenofos (CAS 41198-08-7) technical grade with in-house quality control. Standard CoA testing covers active ingredient assay by GC, sulfoxide impurity, physical appearance, density, and water content. Documentation package includes batch CoA, current GHS-compliant SDS, and complete export paperwork.
 
Minimum order: 25 kg. Standard packaging: steel drums. Volume pricing for full container load quantities. Lead time 7 to 14 business days depending on order size and current production schedule.
 

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