Tween 80 CAS 9005-65-6
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid CAS 7365-44-8
15/07/2025
Best Ethylenediaminetetraacetic Acid [EDTA] CAS 60-00-4
11/07/2025
Name: Tween 80
CAS: 9005-65-6
Purity: 99%min
MOQ: 1KG
Basic Info:
| CAS No: | 9005-65-6 |
| Name: | Tween 80 |
| EINECS: | 500-019-9 |
| Formula: | C24H44O6 |
| Weight: | 428.600006103516 |
| Other Names: | Polysorbate 80; PS80 |
| Type: | Surfactants; Food additives; Dye additives; APIs |
| Shelf Life: | 3 years |
| Brand Name: | Look Chem |
| Place of Origin: | Shandong, China |
Product Introduction:
Tween 80 is a synthetic nonionic emulsifier extensively used in cosmetics, food and pharmaceutical preparations.
This sort of emulsifier was first created by ICI in the United States. Tween is the brand name provided by ICI to this sort of emulsifier, and different numbers are given according to the different sorts of fatty acids made use of in the synthesis process to form a complete trade name, such as Tween 60, Tween 80, etc.
Due to its broad application and very easy memory, Tween has actually become a common brand name for polysorbates in the industry.
There are 5 types of commercialized polysorbates: polysorbate 20, polysorbate 40, polysorbate 60, polysorbate 65, and polysorbate 80, which are additionally frequently called Tween 20, Tween 40, Tween 60, Tween 65, and Tween 80.
Tween is a light off-white to light yellow paste or thick oily fluid at space temperature. It has a special oily scent and a somewhat bitter preference. Tween has great thermal stability. Given that the long chain of polyoxyethylene comprises the hydrophilic group, the hydrophilic team accounts for most of the whole emulsifier particle. Therefore, Tween has a high hydrophilic residential or commercial property and HLB worth and belongs to the O/W kind emulsifier. Its surface area activity is not affected by the environmental pH. At a very low concentration (0.05%), it can considerably decrease the interfacial tension of the soybean oil/water system.
Tween itself is water-soluble, and it has an excellent solubilizing result on lipophilic compounds that are difficult to liquify in water. It can be made use of to prepare emulsified tastes. It also has an excellent oygenation and stirring foaming impact in food. It has a great maintaining impact on particular oil crystals.
Nature and Specifications:
Specification
Product Nature
Specification
| Item | Specification |
| Product Name | Tween 80 |
| CAS No. | 9005-65-6 |
| Appearance | Yellow liquid |
| Shelf Life | 2 years |
| Packing | 1kg/bag,25kg/bag or as your requirements |
Product Nature
- Density: 1.08 g/mL at 20 °C
- Boiling point: >100°C
- Melting point: -25 °C
- Flash point: >230 °F
- Storage temp: -20°C
- Solubility: DMSO (Soluble), Methanol (Slightly)
Product Packaging
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Tween 80 Uses:
Polysorbate 80 is a nonionic surfactant and emulsifier commonly used in pharmaceuticals, foods, and cosmetics. This synthetic compound is a viscous, yellow liquid that is soluble in water.
Food
Polysorbate 80 is used as an emulsifier in food, but studies have shown that it may significantly affect gut microbiota in a way that promotes intestinal inflammation and related disease states.For example, adding a concentration of up to 0.5% (v/v) of polysorbate to ice cream can make it smoother, easier to handle, and enhance its resistance to melting. Adding polysorbate can prevent milk protein from completely enveloping fat droplets. This allows fat droplets to connect into chain like and mesh like structures, retaining air in the mixture and making the texture of ice cream firmer, even when melted, maintaining its shape.
- Health and beauty
Polysorbate 80 can also be used as a surfactant in soap and cosmetics (including eye drops), or as a solubilizer in products such as mouthwash. The impurity content of cosmetic grade polysorbate 80 may be higher than that of food grade polysorbate 80. Clinical
Polysorbate 80 is a surfactant and solubilizer made use of in various dental and topical pharmaceutical products.Polysorbate 80 is additionally an excipient made use of to maintain liquid formulas of medicines for parenteral administration and as an emulsifier in the manufacture of the antiarrhythmic drug amiodarone. It is also used as an excipient for some European and Canadian influenza vaccines. Each dose of influenza vaccination consists of 2.5 μ g of Polysorbate 80. Several vaccinations used in the USA include Polysorbate 80, consisting of the Janssen COVID-19 injection. It is utilized to cultivate Mycobacterium consumption in Middlebrook 7H9 broth. It is additionally used as an emulsifier for the estrogen regulating medication Estrasorb.
Polysorbate 80 is likewise made use of for granulation, stabilizing medicines and excipients when combined with IPA.
Laboratory
Some mycobacteria consist of a lipase (an enzyme that can break down lipid particles); When these varieties are contributed to a blend of polysorbate 80 and phenol red, they cause the service to blemish, making them ideal for examining the phenotype of microbial pressures or isolates.On RODAC agar plates made use of for microbial control, polysorbate 80 can reduce the effects of usual anti-bacterials on tasting surfaces, therefore advertising microbial growth on these surface areas.
Polysorbate 80, chemical name polyoxyethylene 20 sorbitan monooleate, is a nonionic surfactant with significant adaptability to different pH values. It is also relatively stable when coexisting with high concentrations of electrolytes. Its hydrophilic-lipophilic balance (HLB value) is 15, and it is highly hydrophilic. It can be miscible with water, methanol, ethanol, chloroform, and ethyl acetate. It is widely used in injections and oral preparations as an O/W (oil-in-water) emulsifier, solubilizer, and wetting agent.
Studies have shown that when polysorbate 80 reaches a certain critical micelle concentration, the hydrophobic parts of its molecules attract each other and combine together to form micelles. The micelles are spherical bodies formed by the lipophilic groups facing inward and the hydrophilic groups facing outward. The solubilized substances combine with the micelles in different ways, thereby increasing the dissolution of the drug components, but the solubilization effect is different from the true dissolution effect.
Factors affecting solubilization effect
For polar and semi-polar drugs, the larger the HLB value of the non-ionic solubilizer, the more obvious its solubilization effect.
The larger the molecular weight of the solubilized drug, the smaller the solubilization amount is usually, because the volume of the micelle formed by the solubilizer is generally constant, and the larger the molecular weight of the drug, the larger the molar volume. When the concentration of the solubilizer is constant, the less drug can be solubilized.
Some poorly soluble ingredients, such as aconitine extracted from Aconitum, puerarin, baicalin, tanshinone, emodin, various fat-soluble vitamins, and volatile oil components, are difficult to make into liquid preparations. Adding polysorbate 80 can produce a clear liquid preparation with a higher concentration suitable for treatment needs. However, for long-chain poorly soluble drug components, polysorbate 80 has a greater solubilization due to its greater surface activity and follows the law of similar dissolution; for single-ring and double-ring poorly soluble drug components without long chains, it has a poor solubilization effect.
Related References:
- Naimi, S, Viennois, E, Gewirtz, A T, Chassaing, B (2021). “Direct impact of commonly used dietary emulsifiers on human gut microbiota”. Microbiome.
- “Laboratory Use of Polysorbate 80”. Cape Crystal Brands.
Tween 80 Manufacturer & Supplier
As an experienced Tween 80 manufacturer and supplier, Look Chemical is committed to producing and selling high quality products.
We cooperate and trade with 6000+ factories around the world, and our high-quality products and excellent services make us enjoy a high reputation internationally.
As Tween 80 supplier, Look Chemical provides supply chain solutions to partners and customers in a wide range of industries. We offer competitive pricing and quality products.
If you have a demand for this product, please contact our company’s sales staff, we will provide you with a solution in the shortest time.
Our Promise:
Achievements
Service
FAQ
Advice on Shipping
Achievements
I’m william, CEO of Look Chemical Co., Ltd. Welcome to visit our company. As China’s top Global Supply Specialist of chemicals, we have always been adhering to the principle of “service first, quality first, mutual benefit”, and we insist on Create value for customers and grow together with customers.
In the past few years , we have provided efficient and satisfactory services to more than 6000 customers and have been widely praised internationally. In the future, we will strive to provide more than 100,000 customers with professional and thoughtful services, and strive to become your first choice for worry-free purchasing chemicals in China , Hope to bring you a good cooperation experience. If you have any questions, please feel free to contact us.
Service
Pre-Sales Service
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
FAQ
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
Advice on Shipping
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Product Data:
1. Certificate Of Analysis (COA)
2. Material Safety Data Sheet (MSDS)
3. Route of synthesis (ROS)
4. Method of Aanlysis (MOA)
5. Nuclear Magnetic Resonance (NMR)
6. Packing pictures and loading video before loading
7. Free Sample
8. Factory audit
