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Products Description

Name: P-Hydroxyacetophenone

Cas: 99-93-4

Purity: 99%min


Basic Info:

CAS No.:






Stock Availability

In stock

Brand Name

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Product Introduction:

P-Hydroxyacetophenone, also known as 4-Hydroxyacetophenone, 4-Acetylphenol, commonly known as acitrin.

It is white needle-like crystal at room temperature, flammable, easily soluble in hot water, methanol, ethanol, ether, acetone, benzene, and insoluble in petroleum ether.

It naturally exists in the stems and leaves of the Compositae plant, Artemisia annua L., and the roots of plants such as Artemisia annua L.

Animal experiments show that P-Hydroxyacetophenone can increase the secretion of bile in rats.

At the same time, it can also increase the excretion of solids, bile acid and bilirubin in bile, and has the same effect on liver damage caused by carbon tetrachloride.

P-Hydroxyacetophenone is used in the manufacture of choleretic drugs and other raw materials for organic synthesis.

Product Nature:

  • Density: 1.109
  • Boiling point: 147-148 °C3 mm Hg(lit.)
  • Melting point: 132-135 °C(lit.)
  • Flash point: 166 °C
  • Refractive Index: 1.55773 (109ºC)
  • Water solubility: 10 g/L (22 ºC) Stability: Stable under normal temperatures and pressures.


Product NameP-Hydroxyacetophenone Powder
CAS No.99-93-4
Appearance White crystalline powder
Content99% min
Shelf Life2 years
Packing1kg/bag,25kg/bag or as your requirements

Product Usage:

P-Hydroxyacetophenone is generally used to synthesize pharmaceutical intermediates (α-bromo-p-hydroxyacetophenone, choleretic drugs, antipyretic analgesics, etc.), others (spice, feed, etc.; pesticides, dyes, liquid crystal materials, etc.).

used as a preservative

p-Hydroxyacetophenone is the most safe high-temperature complementary energetic stabilizer in the pharmaceutical sector.

It is often used as a preservative in cosmetics and has no harm to the human body or the skin.

For most cosmetics, to ensure the hygiene and safety within the period of use, no preservatives can be added, but no antiseptic system is required, and the problem of bacteriostasis cannot be ignored.

P-Hydroxyacetophenone is mainly used as a preservative in cosmetics, and has anti-oxidation, sedative and soothing functions, and has synergistic effects when combined with other preservatives.

The role of preservatives is mainly to maintain the freshness of products and to avoid bacterial and fungal infections.

Due to its weak molecular activity, high temperature resistance, melting point of 95-97 °C and boiling point of 296 °C, it is widely used in various liquid medicines and can prolong the shelf life of other active ingredients under high temperature conditions.

Used as pharmaceuticals and intermediates in organic synthesis

It is mainly used to synthesize α-bromo-p-hydroxyacetophenone, which is an important intermediate in the synthesis of selective B1 receptor blocker-atenolol.

P-Hydroxyacetophenone, since its particle contains hydroxyl as well as ketone teams on the benzene ring, is often used as an intermediate in organic synthesis to respond with various other compounds to synthesize several important materials.

Para-hydroxyacetophenone itself is a choleretic drug. It is often used as an auxiliary drug for the treatment of cholecystitis and acute and chronic jaundice hepatitis, but the application must follow the doctor’s advice.

used as a spice

In addition, p-hydroxyacetophenone is also a raw material for fine chemical synthesis, which is mostly used in the synthesis of fragrances.


  1. Experiment on Properties of P-Hydroxyacetophenone – Pharmaceutical Research | 2006.
  2. Polymer-Supported Synthesis: 4-Hydroxyacetophenones – Synfacts | 2020.
  3. Wikipedia


Pre-Sales Service

* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.

* The sample supports testing and inspection.

* Each batch of products will be tested to ensure that its quality meets user needs.

*Packaging can also be made according to customer requirements.

*Any inquiries will be answered by our relevant personnel within 24 hours.

*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.


After-Sales Service

*We will monitor the logistics information in real time and will share the information with you.

* You can consult us at any time if you have any questions about the product, and we will answer you in time.

*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.


1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).

2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).

3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).

4. For high-value products, please choose air or express to ensure the safety of product transportation.


Do you accept sample order?

We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.

How to confirm whether the product quality meets our needs before placing an order?

You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.

What’s your MOQ?

Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Learn more about us

Contact us for the latest quotation and free samples of P-Hydroxyacetophenone Powder.

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