| CAS No: | 643-79-8 |
| Name: | o-Phthalaldehyde |
| EINECS: | 211-402-2 |
| Formula: | C8H6O2 |
| Weight: | 134.13 |
| Other Names: | Phthalaldehyde |
| Type: | Electronic Chemicals |
| Shelf Life: | 1 years |
| Brand Name: | Look Chem |
| Place of Origin: | Shandong, China |
o-Phthalaldehyde (commonly abbreviated as OPA, CAS: 643-79-8), systematically designated as 1,2-Benzenedicarboxaldehyde, is a clear-to-pale-yellow crystalline aromatic compound containing two adjacent formyl groups. Due to its exceptionally fast reaction kinetics with primary amines, OPA serves as a fundamental organic building block across analytical biochemistry, specialized synthesis, and high-performance industrial formulations.
At Shandong Look Chemical Co., Ltd., we manufacture and supply industrial and reagent-grade o-Phthalaldehyde under controlled crystallisation parameters. This ensures low volatility losses, consistent particle distribution, and optimal dissolution rates for downstream liquid compounding or reaction chemistry.
| Item | Specification |
| Product Name | o-Phthalaldehyde |
| CAS No. | 643-79-8 |
| Appearance | Sticky Yellow Powder |
| Shelf Life | 2 years |
| Packing | 1kg/bag,25kg/bag or as your requirements |
Thanks to its dual aldehyde functionality and high reactivity toward nucleophilic nitrogen, o-Phthalaldehyde is widely utilized across several key sectors:
Analytical Reagent & Fluorescent Derivatization:
OPA reacts rapidly with primary amino acids and peptides in the presence of thiols (such as 2-mercaptoethanol or N-acetyl-L-cysteine) to yield highly fluorescent isoindole derivatives. It is a industry-standard reagent for pre-column amino acid profiling via HPLC.
Organic Synthesis & Pharmaceutical Intermediates:
Acts as a versatile precursor for heterocyclic compounds, isoindole rings, benzimidazoles, and specialized active pharmaceutical ingredients (APIs).
Industrial Formulations & Water Treatment Biocides:
Utilized as an active precursor or biocide agent in technical water systems, cooling towers, and specialized surface preservation formulations where rapid microbial control is required.
Diagnostic & Biochemical Assay Kits:
Serves as a vital component in clinical laboratory reagents for protein quantification, enzymatic assays, and amine detection reagents.
Navigating global supply chains requires full traceability and adherence to international chemical management standards. Our production facilities operate under strict quality management frameworks to ensure every shipment meets destination port standards:
ISO 9001:2015 Certification: Full process traceability from raw material intake to final batch packaging.
ISO 14001:2015 & ISO 45001:2018: Environmental management and occupational health compliance in batch operations.
REACH Compliance: Pre-registered / REACH documentation available for European Union buyers.
Global Transport Safety: Full SDS/MSDS classification, UN-approved packaging (UN 2923 / Class 8 Corrosive Solid, Toxic Subrisk, where applicable), and official dangerous goods transportation documentation.
To guarantee lot-to-lot batch consistency, Shandong Look Chemical implements a multi-stage Quality Assurance (QA) protocol within our Jinan and Ningxia testing centers. Every commercial batch undergoes rigorous physical and chemical analysis prior to release.
Purity Determination via High-Performance Liquid Chromatography (HPLC):
Method: Isocratic / Gradient reversed-phase HPLC with UV detection.
Acceptance Criteria: Main peak area $\ge 99.0\%$, individual impurity $\le 0.5\%$.
Moisture & Volatiles Analysis:
Method: Karl Fischer Titration / Loss on Drying (LOD).
Acceptance Criteria: Water content $\le 0.5\%$.
Melting Range Verification:
Method: Automated capillary melting point determination.
Acceptance Criteria: Sharp melting window within 55.0–58.0 °C.
Residue on Ignition (Ash Content):
Acceptance Criteria: $\le 0.1\%$.
Trace Metals Analysis (ICP-MS):
Heavy metal contamination screening for sensitive analytical applications.
A batch-specific Certificate of Analysis (COA), Fourier-Transform Infrared (FTIR) spectrum, and HPLC chromatogram are attached to every commercial shipment.
A: We supply OPA in standard 25 kg fiber drums with double-layer anti-static PE inner bags. For laboratory evaluation or pilot testing, sample sizes of 100g, 500g, and 1 kg are available upon request. Custom packaging can be accommodated under specific agreements.
A: o-Phthalaldehyde is light-sensitive and subject to gradual air oxidation over time. It should be stored in tightly sealed, light-resistant containers in a dry, well-ventilated area, preferably at controlled room temperature ($15^\circ\text{C}$ to $25^\circ\text{C}$) or refrigerated ($2^\circ\text{C}$ to $8^\circ\text{C}$) for prolonged shelf life.
A: Standard inventory is maintained at our Qingdao and Shanghai port warehouses. Regular orders are typically dispatched within 7 to 10 working days following contract confirmation and shipping document verification.
Pubchem–o-Phthalaldehyde
As an experienced producer and supplier of o-Phthalaldehyde, Look Chemical is committed to producing and selling high-quality products.
We cooperate and trade with over 6000 factories worldwide, and our high-quality products and services have earned us a high reputation internationally.
As a supplier of o-Phthalaldehyde, Look Chemical provides supply chain solutions to partners and customers in various industries. We offer highly competitive prices and high-quality products.
If you have a demand for this product, please contact our sales staff and we will provide you with a solution as soon as possible.
I’m william, CEO of Look Chemical Co, Ltd. Welcome to visit our company. As China’s top Global Supply Specialist of chemicals, we have always been adhering to the principle of “service first, quality first, mutual benefit”, and we insist on Create value for customers and grow together with customers.
In the past few years , we have provided efficient and satisfactory services to more than 6000 customers and have been widely praised internationally. In the future, we will strive to provide more than 100,000 customers with professional and thoughtful services, and strive to become your first choice for worry-free purchasing chemicals in China , Hope to bring you a good cooperation experience. If you have any questions, please feel free to contact us.
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* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
Advice on Shipping✈️
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
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