L-Proline CAS 147-85-3

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1-Aminocyclopropanecarboxylic Acid CAS 22059-21-8
26/05/2025
1676-75-1
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L-Proline
L-Proline

Base Info:

Name: L-Proline

CAS: 147-85-3

Purity: 99.5%min

MOQ: 1KG

Product Paramete

CAS No:147-85-3
Name:L-Proline
EINECS:205-702-2
FormulaC5H9NO2
Weight115.13
Brand NameLook Chemical
Place of OriginChina
Other Names:L-2-Pyrrolidinecarboxylic acid
Type:Food additives; Plant extracts; Pharmaceutical intermediates; API
Product Model:LC-147-85-3
Shelf Life3 Years
UsageFor food additives
FormLiquid

What is L-Proline?

L-proline is a white crystalline powder at room temperature and pressure, with a slight odor and sweetness. This substance has strong hygroscopicity and responds with hydrated indene ketone to generate a yellow shade. After being acidified with antarctic acetic acid, it appears red. L-proline is just one of the twenty amino acids in the human body, a crucial amino acid for manufacturing human proteins, a crucial basic material for amino acid infusion, and a major intermediate for manufacturing first-line antihypertensive medicines such as Captopril and Enalapril. It has been extensively used in industries such as food and medicine.

Proline was first isolated by Richard Willst ä tter in 1900. He got this amino acid while researching N-methylproline and synthesized proline by responding the sodium salt of diethyl malonate with 1,3-dibromopropane. The following year, Emil Fischer isolated proline from the decomposition items of casein and γ – phthalimide propyl malonate, and released an article on the synthesis of proline making use of phthalimide propyl malonate as a raw material.

The name proline originates from among its components, pyrrolidine.

Physical Properties

Product Packaging

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L-Proline Uses

Amino acids are a general term for a course of organic compounds including amino and carboxyl groups. The visibility of amino acids in the body not just offers a crucial resources for manufacturing healthy proteins, however also offers a product basis for promoting growth, regular metabolic process, and keeping life. The major uses of L-proline are as adheres to:

  1. As an amino acid, it can supplement nutrients and is the raw material for amino acid infusion.
  2. It is effective for hypertension and is an important intermediate for synthesizing first-line antihypertensive drugs such as captopril and enalapril.
  3. L-proline and sugar are heated together to produce amino acid-carboxyl reactions to generate substances with special aromas.
  4. As a nutritional supplement, it can improve tissue resistance and increase callus survival rate.
  5. It can effectively alleviate the damage to the mitochondrial structure of rice regeneration plants caused by salt stress.

Applications of L-Proline

L-proline can be used as an intermediate in organic synthesis and pharmaceutical chemistry, and can be used in the synthesis and production of antihypertensive drug molecules captopril and enalapril. Captopril is mainly used as an angiotensin transferase inhibitor. It is used to treat hypertension and certain types of congestive heart failure. It is used to treat various types of hypertension, especially refractory hypertension that is ineffective with other antihypertensive drugs. It can be used in combination with diuretics to enhance the efficacy, and it is more effective for patients with high plasma renin activity.

This compound is likewise made use of for severe and chronic heart disease, and it is extra effective when made use of in combination with cardiotonic representatives or diuretics. Enalapril is an angiotensin converting enzyme prevention (ACEI). After dental management, it is hydrolyzed into enalaprilat in the body, which highly inhibits angiotensin transforming enzyme, reduces the material of angiotensin II, triggers systemic vasodilation, and lowers blood pressure. It is utilized to deal with hypertension.

L-proline is a chiral amino acid that can be used in the manufacturing of amino acid shots and substance amino acid mixtures, and can likewise be used as a preservative and dietary supplement. Additionally, it likewise has particular applications in fundamental biochemical research.

L-proline can be utilized for poor nutrition, protein shortage, gastrointestinal illness, and postoperative healthy protein supplements, and so on. As a dietary supplement, it can be heated up with sugar to generate an aminocarbonyl reaction to generate a special taste material that can be used as a flavoring.

Product Data

1. Certificate Of Analysis (COA)

2. Material Safety Data Sheet (MSDS)

3. Route of synthesis (ROS)

4. Method of Aanlysis (MOA)

5. Nuclear Magnetic Resonance (NMR)

6. Packing pictures and loading video before loading

7. Free Sample

8. Factory audit

L-Proline Manufacturer & Supplier

As an experienced L-Proline manufacturer and supplier, Look Chemical is committed to producing and selling high quality products.

We cooperate and trade with 6000+ factories around the world, and our high-quality products and excellent services make us enjoy a high reputation internationally.

As L-Proline supplier, Look Chemical provides supply chain solutions to partners and customers in a wide range of industries. We offer competitive pricing and quality products.

If you have a demand for this product, please contact our company’s sales staff, we will provide you with a solution in the shortest time.

Service

Pre-Sales Service

  • Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
  • The sample supports testing and inspection.
  • Each batch of products will be tested to ensure that its quality meets user needs.
  • Packaging can also be made according to customer requirements.
  • Any inquiries will be answered by our relevant personnel within 24 hours.
  • We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.

After-Sales Service

  • We will monitor the logistics information in real time and will share the information with you.
  • You can consult us at any time if you have any questions about the product, and we will answer you in time.
  • If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.

Loading and Transportation

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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Related References

  1. Miao Zhengxing, Zhang Zhongming, Li Baozhong. Production and application of L-proline[J]. Fermentation Science and Technology Newsletter
  2. PubChem