High Quality Isotonitazene CAS 14188-81-9

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Isotonitazene
14188-81-9

Products Description

Name: Isotonitazene

Cas: 14188-81-9

Purity: 99%min

MOQ: 1KG

Basic Info:

CAS No:

14188-81-9

Formula:

C23H30N4O3

EINECS:

200-533-0

Stock Availability

In stock

Brand Name

Look chem

Origin

China

 

Product Introduction:

Isotonitazene is chemically called diethyl-{2-[2-(4-isopropoxy-benzyl)-5-nitro-benzoimidazol-1-yl]-ethyl}-amine.

Synthetic opioids containing the core of Isotonitazene and other chemically synthesized benzimidazoles, such as etolidine, clonidazole, etc., were first reported in the late 1950s.

Isotonitazene is an opioid analgesic derived from the benzimidazole related to etonitagen and is currently sold as a prescription drug.

Although the potency of Isotonitazene in animal studies is only about half that of etolazone, its potency in humans may not be as good as before with etolazone (in animal models it is 1,000 times more potent than morphine, but its potency in humans is only 1000 times that of morphine. Is 60 times that of morphine).

Product Nature:

  • Boiling point: 584.7±45.0 °C(Predicted)
  • Density: 1.16±0.1 g/cm3(Predicted)
  • Acidity coefficient (pKa): 9.91±0.25(Predicted)

Specification:

ItemSpecification
Product NameIsotonitazene Powder
CAS No.14188-81-9
Appearance White powder
Content99% min
Shelf Life2 years
Packing1kg/bag,25kg/bag or as your requirements

Pharmacological Action:

Data from preclinical studies indicate that the pharmacological profile of Isotonitazene is similar to that of etoprazine and other μ-opioid receptor agonists.

In in vivo (mice) studies, Isotonitazene was more effective than morphine as an analgesic in the tail-flick test.

Data from in vitro (mouse) studies indicate that fentanyl is similar to hydromorphone Isotonitazene and can activate μ-opioid receptors.

It has been reported that the activation of the μ-opioid receptor by Isotonitazene involves the recruitment of the regulatory protein β-arrestin-2.

Studies have shown that the interaction of μ-opioid receptors and β-arrestin-2 is related to some side effects of opioid analgesics.

Naloxone is an opioid receptor antagonist that blocks isotope-induced μ-opioid receptor activation.

These data indicate that Isotonitazene, similar to fentanyl and other μ-opioid receptor agonists, can bind to and activate μ-opioid receptors.

It is well known that Isotonitazene is a μ-opioid receptor agonist, which is highly addictive and can induce dose-dependent respiratory depression.

References:

Service:

Pre-Sales Service

* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.

* The sample supports testing and inspection.

* Each batch of products will be tested to ensure that its quality meets user needs.

*Packaging can also be made according to customer requirements.

*Any inquiries will be answered by our relevant personnel within 24 hours.

*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.

 

After-Sales Service

*We will monitor the logistics information in real time and will share the information with you.

* You can consult us at any time if you have any questions about the product, and we will answer you in time.

*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.

Shipping:

1. ≤50kg, we recommend express delivery, usually called DDU service;

2. ≤500kg, air transportation is generally recommended, usually called FOB, CFR or CIF service;

3.>500kg, sea freight is generally recommended, usually called FOB, CFR or CIF service;

4. For high-value products, please choose air and express to ensure the safety of the products.

FAQ

Do you accept sample order?

We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.

How to confirm whether the product quality meets our needs before placing an order?

You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.

What’s your MOQ?

Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Learn more about us

Contact us for the latest quotation and free samples of Isotonitazene Powder

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Packaging and shipping

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Isotonitazene
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