High purity Pterostilbene 99% CAS 537-42-8 | Extract

As an antioxidant, pterostilbene can resist cell proliferation, lower blood lipids, and inhibit COX-1 and COX-2, anticancer and antifungal.

1. Colorectal Cancer
   • Colorectal cancer is one of the most common malignant tumors in people in their 40s and 50s. According to a global epidemiological survey, colon cancer has the highest incidence in North America, Western Europe, Australia, New Zealand and other regions, and ranks second in visceral tumors.
   • After years of animal testing, American scientists have discovered that this compound from blueberries and grapes can inhibit an enzyme called “P450 cytochrome,” which can activate chemical carcinogens, and can reduce low-density lipoprotein cholesterol. cancer and heart disease.
   • Pterostilbene is a type of aromatic fragrance named “styrene” hydrocarbon, a derivative of resveratrol. In the early 1990s, American scientists discovered that resveratrol had the ability to prevent breast cancer and heart disease and was abundant in red grape skins.
   • Pterostilbene helps prevent precancerous damage in the body. It is found in blueberries and blackberries as antioxidants and anti-inflammatory agents. According to Ohio State University, animals that eat brownberry berries have an 80% lower risk of colon cancer and a 60% lower risk of developing gastrointestinal tumors. Colorectal cancer can also be treated.
   • Statistics show that after 8 weeks of continuous consumption of blueberries or grapes containing pterostilbene, there was a 57% reduction in colonic precancerous lesions. It can reduce the spread of bowel cancer cells and inhibit certain genes that cause inflammation. Both are considered risk factors for colorectal cancer.
2. If you have a skin tumor
   
   • Skin tumors are one of the most common human tumors in scope. Epidemiological data show that UV radiation is a major carcinogen of skin tumors. UV irradiation stimulates the proliferation of abnormal skin cell clones, making the cells cancerous through multiple signaling pathways.
   • Many plant compounds have inhibitory effects on chemically induced mouse skin tumors, such as resveratrol and grape seed extract. It controls the survival of intermediate cell biomarkers by inhibiting epidermal proliferation and cell proliferation, and suppresses the development of skin tumors by reducing the inflammatory marker COX-2, oncogene mutations and apoptosis.
   • Resveratrol can reduce dermal papillomas in mice induced by dimethylbenzanthracene/croton oil by 60%. Prolonged latency of tumorigenesis, reduced incidence of papillomas, increased number of tumors per mouse, decreased in a dose-dependent manner.
   • Pterostilbene inhibits the growth of cancer cells by changing the cell cycle, induces apoptosis, and inhibits tumor growth and metastasis in vivo. In addition, pterostilbene and resveratrol can enhance the expression of antioxidant enzymes such as heme oxygenase-1 and glutathione reductase by significantly activating Nrf2. Pterostilbene can also induce tumor cell death through lysosomal membrane permeability.
   • Melanoma has become a highly malignant skin tumor due to its aggressiveness, early metastasis, and high mortality. Pterostilbene and quercetin inhibit the growth and metastasis of metastatic melanoma. The mechanism inhibits the expression of adhesion molecule 1 in murine hepatic sinusoidal endothelial cells to reduce adhesion of B16M-F10 cells to endothelial cells and metastatic cells Bcl-2 to suppress expression. Reduces cytotoxicity of vascular endothelial cells.
   • At the same time, Pterostilbene significantly inhibits skin tumors induced by NF-κB and active protein 1 activation.
3. Anti-inflammatory
   
   • Pterostilbene stimulates neutrophils by activating reduced coenzyme II oxidase through protein kinase C, thereby preventing the formation of superoxide superoxide anion and myeloperoxidase.
   • Pterostilbene has the ability to inhibit the activation of nuclear factor NF-κB, thereby inhibiting the activation of pro-inflammatory cytokines and nitric oxide synthase genes. reduces the stimulus response to