High purity Pterostilbene 99% CAS 537-42-8 | Extract

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Pterostilbene
537-42-8

Products Description

Name: Pterostilbene

Cas: 537-42-8

Purity: 99%min

MOQ: 1KG

Basic Info:

CAS No.:

537-42-8

Formula:

C16H16O3

EINECS:

611-041-4

Stock Availability

In stock

Brand Name

Look chem

Origin

China

 

Product Introduction:

pterostilbene, alias 3,5-dimethoxy-4′-hydroxystilbene, (E)-3,5-dimethoxy-4′-hydroxystyrene, (E)-4-[2-(3) ,5-dimethoxyphenyl)-vinyl]-phenol and 4-[(1E)-2-(3,5-dimethoxyphenyl)-vinyl]-phenols, derived from plants such as sandalwood, blueberries, grapes, and palm trees. It is a kind of active ingredient.

Pterostilbene is a white or almost white powdery crystal with rich medicinal value, and belongs to the antifungal active ingredient of Dragon’s blood products, and has a certain effect on the treatment of cancer, high blood pressure and hyperlipidemia.

Pterostilbene has anti-cancer, anti-inflammatory, antioxidant and analgesic effects. Numerous studies have shown that Pterostilbene is good for the treatment and protection of skin diseases, especially in the field of antioxidants.

Product Nature:

  • Melting point: 89-92 ºC
  • Boiling point: 420.4±35.0 °C(Predicted)
  • Density: 1.169±0.06 g/cm3(Predicted)
  • Storage conditions: 2-8°C
  • Solubility: DMSO: >20mg/mL

Specification:

ItemSpecification
Product NamePterostilbene
CAS No.537-42-8
Appearance White crystalline powder
Content99% min
Shelf Life2 years
Packing1kg/bag,25kg/bag or as your requirements

Product function:

As an antioxidant, pterostilbene can resist cell proliferation, lower blood lipids, and inhibit COX-1 and COX-2, anticancer and antifungal.

  1. Colorectal Cancer
    • Colorectal cancer is one of the most common malignant tumors in people in their 40s and 50s. According to a global epidemiological survey, colon cancer has the highest incidence in North America, Western Europe, Australia, New Zealand and other regions, and ranks second in visceral tumors.
    • After years of animal testing, American scientists have discovered that this compound from blueberries and grapes can inhibit an enzyme called “P450 cytochrome,” which can activate chemical carcinogens, and can reduce low-density lipoprotein cholesterol. cancer and heart disease.
    • Pterostilbene is a type of aromatic fragrance named “styrene” hydrocarbon, a derivative of resveratrol. In the early 1990s, American scientists discovered that resveratrol had the ability to prevent breast cancer and heart disease and was abundant in red grape skins.
    • Pterostilbene helps prevent precancerous damage in the body. It is found in blueberries and blackberries as antioxidants and anti-inflammatory agents. According to Ohio State University, animals that eat brownberry berries have an 80% lower risk of colon cancer and a 60% lower risk of developing gastrointestinal tumors. Colorectal cancer can also be treated.
    • Statistics show that after 8 weeks of continuous consumption of blueberries or grapes containing pterostilbene, there was a 57% reduction in colonic precancerous lesions. It can reduce the spread of bowel cancer cells and inhibit certain genes that cause inflammation. Both are considered risk factors for colorectal cancer.
  2. If you have a skin tumor
    • Skin tumors are one of the most common human tumors in scope. Epidemiological data show that UV radiation is a major carcinogen of skin tumors. UV irradiation stimulates the proliferation of abnormal skin cell clones, making the cells cancerous through multiple signaling pathways.
    • Many plant compounds have inhibitory effects on chemically induced mouse skin tumors, such as resveratrol and grape seed extract. It controls the survival of intermediate cell biomarkers by inhibiting epidermal proliferation and cell proliferation, and suppresses the development of skin tumors by reducing the inflammatory marker COX-2, oncogene mutations and apoptosis.
    • Resveratrol can reduce dermal papillomas in mice induced by dimethylbenzanthracene/croton oil by 60%. Prolonged latency of tumorigenesis, reduced incidence of papillomas, increased number of tumors per mouse, decreased in a dose-dependent manner.
    • Pterostilbene inhibits the growth of cancer cells by changing the cell cycle, induces apoptosis, and inhibits tumor growth and metastasis in vivo. In addition, pterostilbene and resveratrol can enhance the expression of antioxidant enzymes such as heme oxygenase-1 and glutathione reductase by significantly activating Nrf2. Pterostilbene can also induce tumor cell death through lysosomal membrane permeability.
    • Melanoma has become a highly malignant skin tumor due to its aggressiveness, early metastasis, and high mortality. Pterostilbene and quercetin inhibit the growth and metastasis of metastatic melanoma. The mechanism inhibits the expression of adhesion molecule 1 in murine hepatic sinusoidal endothelial cells to reduce adhesion of B16M-F10 cells to endothelial cells and metastatic cells Bcl-2 to suppress expression. Reduces cytotoxicity of vascular endothelial cells.
    • At the same time, Pterostilbene significantly inhibits skin tumors induced by NF-κB and active protein 1 activation.
  3. Anti-inflammatory
    • Pterostilbene stimulates neutrophils by activating reduced coenzyme II oxidase through protein kinase C, thereby preventing the formation of superoxide superoxide anion and myeloperoxidase.
    • Pterostilbene has the ability to inhibit the activation of nuclear factor NF-κB, thereby inhibiting the activation of pro-inflammatory cytokines and nitric oxide synthase genes. reduces the stimulus response to

Safety instructions:

In case of accidental contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear goggles or a mask. Avoid release to the environment. See special instructions/safety data sheet. Serious damage to the eyes. Toxic to aquatic life and may cause long-term adverse effects in the aquatic environment.

References:

  1. “Pterostilbene’s healthy potential”. US Department of Agriculture, Online Magazine, Vol. 54, No. 11. 1 November 2006. Retrieved 2016-03-21.
  2. Wikipedia

Service:

Pre-Sales Service

* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.

* The sample supports testing and inspection.

* Each batch of products will be tested to ensure that its quality meets user needs.

*Packaging can also be made according to customer requirements.

*Any inquiries will be answered by our relevant personnel within 24 hours.

*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.

 

After-Sales Service

*We will monitor the logistics information in real time and will share the information with you.

* You can consult us at any time if you have any questions about the product, and we will answer you in time.

*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.

Shipping:

1. ≤50kg, we recommend express delivery, usually called DDU service;

2. ≤500kg, air transportation is generally recommended, usually called FOB, CFR or CIF service;

3.>500kg, sea freight is generally recommended, usually called FOB, CFR or CIF service;

4. For high-value products, please choose air and express to ensure the safety of the products.

FAQ

Do you accept sample order?

We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.

How to confirm whether the product quality meets our needs before placing an order?

You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.

What’s your MOQ?

Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Learn more about us

Contact us for the latest quotation and free samples of Pterostilbene

Get a quote

Packaging and shipping

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