Best Hexafluoroisopropanol (HFIP) CAS 920-66-1

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Products Description

Name: Hexafluoroisopropanol

Cas: 920-66-1

Purity: 99%min


Basic Info:

CAS No.:






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Product Introduction:

Hexafluoroisopropanol (abbreviation: HFIP), the molecular formula is C3H2F6O, is a viscous, colorless liquid with a pungent odor.

Although HFIP has a certain viscosity but its boiling point is very low, it usually needs to be analyzed at 40°C to reduce the back pressure of the column.

Hexafluoroisopropanol is also a highly polar solvent, which can make calibration curves for mixed-bed columns non-linear.

Hexafluoroisopropanol is a volatile (boiling point 58.2°C) and polar substance with high density, low viscosity and low surface tension

Therefore, Agilent has developed a special column for Hexafluoroisopropanol solvent – PLHFIPgel column, which has a porous structure that is not affected by the solvent.

Product Nature:

  • Density: 1.596
  • Boiling point: 59ºC
  • Melting point: -4ºC
  • Refractive index: 1.274-1.277
  • Flash point: 4,4°C
  • Vapor pressure: 269 hPa (30 °C)
  • Stability: Stable. Incompatible with strong acids, strong bases and alkali metals.


Product NameHexafluoroisopropanol (HFIP) Powder
CAS No.920-66-1
Appearance Colorless transparent viscous liquid
Content99% min
Shelf Life2 years
Packing1kgs/drum,25kgs/drum or as your requirements

Product Usage:

Hexafluoroisopropanol (abbreviation: HFIP) is an important fluorine-containing fine chemical and a new type of fluorine-containing compound.

Hexafluoroisopropanol is used as an intermediate for pharmaceuticals, it can synthesize the inhalation anesthetic sevoflurane, and it is also an intermediate for the synthesis of agricultural chemicals.

Hexafluoroisopropanol can be used to prepare various fluorine-containing chemicals such as fluorine-containing surfactants, fluorine-containing emulsifiers, and fluorine-containing medicines, or as a good solvent.

And it is a highly polar solvent, easy to mix with water and many organic solvents, good thermal stability, and good transmittance to ultraviolet light.

Hexafluoro-2-propanol can be used as a liquid peptide chemical solvent, a highly soluble solvent for peptides and peptide intermediates, etc.

Hexafluoroisopropanol can dissolve a large portion of polymers such as polyester, polyamide, polyacrylonitrile, polyacetal and hydrolyzed polyvinyl ester.

Due to this property, it can be well used in analysis and as a regenerant for polymer reuse.

The efficiency of rhodium(I)-catalyzed [4+2] intramolecular cycloaddition of ether-bound alkynyldiene and [5+2] cycloaddition of alkynylvinylcyclopropane can be improved.

HFIP can also be used for the analysis of a variety of polymers.


  1. Bis XH-π Interactions of Hexafluoroisopropanol with Aromatic Hydrocarbons – PMC | 2021 Jul 28.
  2. The Master List of PFAS Substances (2nd Edition)” – U.S. Environmental Protection Agency | January 21, 2022.
  3. Wikipedia


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*Packaging can also be made according to customer requirements.

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After-Sales Service

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*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.


1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).

2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).

3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).

4. For high-value products, please choose air or express to ensure the safety of product transportation.


Do you accept sample order?

We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.

How to confirm whether the product quality meets our needs before placing an order?

You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.

What’s your MOQ?

Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

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