Gossypol-Acetic Acid CAS 12542-36-8
Gossypol-Acetic Acid CAS 12542-36-8 | API
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Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union
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Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
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Min: 10 Gram
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Delivery: 7 Days
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Transporta: Ocean, Land,Air, DHL，TNT
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Port: Shanghai Port, Qingdao Port
Name: Gossypol-Acetic Acid
CAS: 12542-36-8
Purity: 99%min
MOQ: 1KG
Chemical Structure
Basic Info:
| CAS No: | 12542-36-8 |
| Name: | Gossypol-Acetic Acid |
| EINECS: | 623-939-3 |
| Formula: | C32H34O10 |
| Weight: | 578.61 |
| Other Names: | Acetate Gossypol |
| Type: | API |
| Brand Name: | Look Chem |
| Place of Origin: | Shandong, China |
Basic Introduction to Gossypol-Acetic Acid
Gossypol-acetic acid (CAS No. 12542-36-8; Molecular Formula:C32H34O10; Molecular Weight: 578.61 g/mol) is a naturally derived polyphenolic adduct formed by the stoichiometric 1:1 complexation of pure gossypol (isolated from Gossypium cottonseed) with glacial acetic acid. The formation of this crystalline acetate adduct stabilizes the highly reactive dialdehyde polyphenolic core of free gossypol, effectively mitigating spontaneous oxidative degradation and enhancing chemical stability during processing and storage.
Shandong Look Chemical Co., Ltd. manufactures stabilized, high-assay Gossypol-acetic acid engineered for demanding pharmaceutical synthesis and targeted biochemical research. Because polyphenolic compounds require strict contamination controls, our production workflow combines low-temperature plant extraction with multi-stage preparative crystallization. This ensures precise molar stoichiometry, low residual solvent levels, and strict enantiomeric reproducibility for oncology screening, male contraceptive research, and enzyme inhibition studies.
Nature and Specifications:
Specification
Specification
| Item | Specification |
| Product Name | Gossypol-Acetic Acid |
| CAS No. | 108-46-3 |
| Appearance | Dark Yellow Solid |
| Shelf Life | 2 years |
| Packing | 1kg/bag,25kg/bag or as your requirements |
Product Packaging
Gossypol-Acetic Acid Application
Gossypol-acetic acid’s polyphenolic structure, featuring binaphthyl chirality and dual aldehyde groups, serves as a versatile chemical intermediate across several high-value sectors:
A. Active Pharmaceutical Ingredient (API) Intermediate & Drug Discovery
Bcl-2 Family Protein Inhibitors: Serves as a fundamental reference compound and precursor in apoptosis research, specifically targeting Bcl-2 and Bcl-xL anti-apoptotic proteins in targeted therapeutic screening.
Reproductive Medicine & Hormone Research: Utilized as a standard active ingredient in scientific studies evaluating non-hormonal male fertility regulation and spermatogenesis inhibition mechanisms.
B. Enzymatic & Antiviral Research
Enzyme Inhibition Studies: Functions as a selective inhibitor in laboratory research examining nuclear enzymes, dehydrogenases, and cellular energy pathways.
Antiviral Screening Intermediates: Employed as a key precursor in evaluating small-molecule interactions against viral replication enzymes and membrane targets.
C. Custom Chemical Synthesis & Derivatization
Chiral Ligand & Schiff Base Synthesis: The reactive aldehyde and hydroxyl groups allow organic chemists to synthesize custom Schiff bases, chiral ligands, and organometallic complexes for specialized catalysis.
Certifications & Regulatory Compliance
To meet the stringent sourcing standards of international pharmaceutical manufacturers, research facilities, and chemical distributors, our facility and logistics framework operate in full alignment with global compliance mandates:
ISO 9001:2015 Quality Management System: Standardized extraction, reaction, and purification workflows ensuring batch-to-batch consistency and traceable documentation.
ISO 14001:2015 Environmental Management: Closed-loop solvent recovery systems designed to minimize volatile organic compound (VOC) emissions during botanical processing.
GHS & SDS Adherence: Fully compliant Safety Data Sheets (16 sections) furnished with correct hazard classification markers (GHS07, GHS08) for international handling.
REACH Compliance Support: Complete technical dossiers, structural confirmation data, and spectral validation for regulatory compliance within the European Single Market.
Inert Packaging & Transport Accreditation: UN-rated light-blocking, moisture-proof aluminum foil packaging with nitrogen flushing protocols to protect heat-sensitive shipments.
At SD Look Chemical, every production batch of Gossypol-acetic acid undergoes rigorous analytical testing prior to release. Our analytical laboratories utilize high-precision instrumentation to verify chemical purity, molar ratio, and heavy metal boundaries.
Standard Certificate of Analysis (COA) Specifications:
Appearance: Fine yellow crystalline powder (Visual Inspection – Conforms)
Assay / Purity (HPLC): ≥ 98.0 % (Typical Batch Result: 98.75 % / HPLC-UV at 254 nm)
Identity (1H-NMR & FT-IR): Conforms to standard structure (Structural Match Verified)
Loss on Drying: ≤ 1.0 % (Karl Fischer / Vacuum Oven at reduced temperature)
Heavy Metals (as Pb): ≤ 10 ppm (ICP-MS)
Residue on Ignition: ≤ 0.2 % (Gravimetric Analysis)
Residual Solvents (Ethanol/Acetic Acid balance): Within ICH Q3C limits (GC-Headspace)
High-Performance Liquid Chromatography (HPLC-UV): Quantitative determination of purity to restrict free uncomplexed impurities and degradants.
Proton Nuclear Magnetic Resonance (1H-NMR): Confirms the exact 1:1 molar complexation between the gossypol core and acetic acid.
Inductively Coupled Plasma Mass Spectrometry (ICP-MS): Verifies sub-ppm limits for heavy metal impurities (Lead, Cadmium, Mercury, Arsenic).
Retention Sampling System: Sealed, dark-stored climate samples from every commercial lot are retained for 24 months to support post-delivery technical verification.
FAQ
A: Free gossypol is unstable and susceptible to rapid oxidation when exposed to air and ambient light. Complexing gossypol with glacial acetic acid in a 1:1 molar ratio forms a stable crystalline adduct, significantly extending shelf life, maintaining assay precision, and improving handling characteristics for analytical and synthetic use.
A: Gossypol-acetic acid is light-sensitive and thermolabile. It must be stored in tightly sealed, light-resistant containers (e.g., amber glass or vacuum-sealed nitrogen-flushed aluminum bags) at refrigerated or freezing temperatures (-15°C to 5°C), kept away from moisture and strong oxidizing agents.
A: Yes. We offer lab-scale research quantities (10g, 50g, 100g, 1kg) up to commercial batch scale (25kg drums). Every order is accompanied by a batch-specific Certificate of Analysis (COA), HPLC chromatogram, and MSDS. NMR and IR spectra are available upon request.
A: Export shipments are sealed under nitrogen in oxygen-barrier aluminum packaging with desiccant packs. For warm-climate destinations or expedited air transit, we utilize insulated thermal packaging with cold packs or dry ice to ensure product integrity upon arrival.
Related References:
Pubchem–Gossypol-Acetic Acid
Gossypol-Acetic Acid Manufacturer & Supplier
As an experienced producer and supplier of Gossypol-Acetic Acid, Look Chemical is committed to producing and selling high-quality products.
We cooperate and trade with over 6000 factories worldwide, and our high-quality products and services have earned us a high reputation internationally.
As a supplier of Gossypol-Acetic Acid, Look Chemical provides supply chain solutions to partners and customers in various industries. We offer highly competitive prices and high-quality products.
If you have a demand for this product, please contact our sales staff and we will provide you with a solution as soon as possible.
Achievements📝
I’m william, CEO of Look Chemical Co, Ltd. Welcome to visit our company. As China’s top Global Supply Specialist of chemicals, we have always been adhering to the principle of “service first, quality first, mutual benefit”, and we insist on Create value for customers and grow together with customers.
In the past few years , we have provided efficient and satisfactory services to more than 6000 customers and have been widely praised internationally. In the future, we will strive to provide more than 100,000 customers with professional and thoughtful services, and strive to become your first choice for worry-free purchasing chemicals in China , Hope to bring you a good cooperation experience. If you have any questions, please feel free to contact us.
Pre-Sales Service👍
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* The sample supports testing and inspection.
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*Packaging can also be made according to customer requirements.
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*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service🔔
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
Advice on Shipping✈️
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Company Info
Look chemical company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
And a range of 30,000 products with the best quality and competitive price to meet your different purchasing needs.
Product Data:
- Certificate Of Analysis (COA)
- Material Safety Data Sheet (MSDS)
- Route of synthesis (ROS)
- Method of Analysis (MOA)
- Nuclear Magnetic Resonance (NMR)
- Packing pictures and loading video before loading
- Free Sample
- Factory audit
