Securing the Source: Why Top Brands Prefer Our High-Purity Folic Acid Powder (CAS 59-30-3)
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Name: Folic Acid Powder
Cas: 59-30-3
Purity: 99%min
MOQ: 1KG
Directory Guidance on Folic Acid
- Basic Information of Folic Acid
- Advanced Manufacturing Technology: Eradicating Traditional Processing Flaws
- Packaging Standards, Global Logistics, and Closed-Loop Post-Sale Support
- Competitive Architecture: How We Compare with Generic Competitors
- Production Scales & Quality Assurance Capabilities
- Related References
- Our Promise
- Loading and Transportation
- Hot Products
- FAQ
Chemical Structure
Basic Info of Folic Acid
Folic Acid (Chemical Name: Pteroylglutamic Acid, CAS Number: 59-30-3), a vital member of the Vitamin B complex (Vitamin B9), functions as an indispensable coenzyme for human cellular growth, DNA synthesis, and amino acid metabolism. On the industrial procurement side, it is widely utilized across dietary supplements, pharmaceutical formulations (APIs), infant nutrition, and premium animal feed grades.
Key Physical & Chemical Metrics
- CAS Registry Number: 59-30-3
- Molecular Formula: C₁₉H₁₉N₇O₆
- Molecular Weight: 441.4 g/mol
- Physical Appearance: Yellow to orange-yellow crystalline powder; odorless and tasteless.
- Solubility Profile: Practically insoluble in water and ethanol; readily soluble in dilute hydrochloric acid, sulfuric acid, or alkaline hydroxides and carbonate solutions.
Application:
FAQ
Q1: Is your Folic Acid Powder (CAS 59-30-3) universally compliant across different regulatory markets like the US, EU, and Asia?
A: Yes, absolutely. Our Folic Acid is manufactured under a “multi-harmonized” quality standard. The finished product simultaneously fulfills the rigid technical criteria of the United States Pharmacopeia (USP), European Pharmacopoeia (EP), British Pharmacopoeia (BP), and Chinese Pharmacopoeia (ChP). We generate targeted analysis sheets matched to your specific target market.
Q2: How does your product optimize powder flowability and processing yields during capsule-filling and tableting?
A: A common challenge with standard folic acid is that it is too light, easily electrostatically charged, and tends to stick to machinery. Our crystal morphology modification significantly boosts bulk density and flowability. Furthermore, by providing specific selections like 325 mesh ultra-fine powder (ideal for infant formulas and liquid suspensions) or 100/200 mesh powder (ideal for direct compression), we save you from extra wet-granulation or milling phases.
Q3: What is your Minimum Order Quantity (MOQ)? Do you provide customized private labeling or packaging?
A: Our standard commercial packaging is 25kg/drum. However, to support new clients through material qualifications, pilot tests, and scale-up validation, we support 1kg and 5kg pilot-tier quantities. For strategic contract buyers, we offer custom drum materials, specialized labeling, or specific tailored granulation distributions.
Advanced Manufacturing Technology: Eradicating Traditional Processing Flaws
Conventional folic acid synthesis often suffers from poorly controlled multi-step reactions, which lead to high levels of colored byproducts, excessive heavy metals, and poor powder flowability. Our internal R&D center has overcome these issues by commercializing a green targeted catalytic synthesis process paired with directional crystal-structure engineering.
- High-Selectivity Three-Component One-Pot Condensation: By executing microsecond-level flow rate control over 2,4,5,6-tetraaminopyrimidine sulfate, p-aminobenzoyl glutamic acid, and trichloroacetone (or equivalent synthons)—backed by a proprietary organic amine catalyst—we push the primary reaction selectivity above 92%. This drastically reduces the formation of Impurity A and Impurity D.
- Multi-Stage Temperature-Controlled Recrystallization: Traditional folic acid tends to form interlocking needle-like crystals, which cause sticking or capping during high-speed tableting. We use an automated heating-cooling profile and seed crystallization to force the crystals into regular, spherical micro-crystals. This radically improves powder flowability and bulk density.
- Membrane Ultrafiltration Purifying System: By combining macro-porous adsorption resins with advanced membrane filtration, we strip hazardous heavy metals (lead, arsenic, cadmium, mercury) down to sub-PPM levels during the refinement phase. Residual organic solvents (e.g., methanol, ethanol) remain far below USP/EP specification limits.
Packaging Standards, Global Logistics, and Closed-Loop Post-Sale Support
1. Moisture-Proof and Photo-Protected Packaging
Folic acid exhibits sensitivity to light and ambient heat. We deploy a triple-layered defense system:
- Inner Layer: Double pharmaceutical-grade, anti-static, vacuum-sealed High-Density Polyethylene (HDPE) bags.
- Outer Layer: 25kg heavy-duty fiber drums, with customizable configurations available for specialized container consolidations.
2. Compliant Multi-Modal Logistics
- While Folic Acid is classified as a non-regulated, general chemical commodity, our documentation team brings over a decade of international freight experience, providing flawless export documentation, commercial invoices, and factory COAs.
- Through long-term volume service agreements with tier-1 ocean liners (FCL/LCL), air cargo carriers, and cross-border rail networks, we guarantee steady, uninterrupted transit straight to your destination port or DDP warehouse.
Product Packaging
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Competitive Architecture: How We Compare with Generic Competitors
Rather than participating in low-margin price wars, our plant establishes a market edge through structural compliance and superior physical properties:
| Performance Metric | Our Factory (Direct Source Manufacturer) | Generic Competitors / Intermediary Processors |
|---|---|---|
| Purity & Pharmacopoeia Limits | Maintained at 97.0% – 102.0% (on dried basis); fully compliant with current USP, EP, BP, and ChP editions. | Purity barely scrapes the legal limit; high batch-to-batch volatility makes it fail international pharmaceutical audits. |
| Particle Size Customization | Available in standard mesh, 80, 100, 200, and 325 ultra-fine mesh, as well as pre-granulated forms. | Only supplies fixed coarse powders; obligates downstream factories to perform milling, increasing contamination risks. |
| Related Substances (Impurities) | Single unknown impurity < 0.1%. Total impurities are kept at industry lows, preventing product discoloration. | Elevated isomer and byproduct residues cause tablets or capsules to discolor over time due to oxidation. |
| Regulatory & Certifications | Certified by GMP, ISO9001, ISO22000, HALAL, and KOSHER; fully supports on-site and remote audits. | Missing core certificates; lacks international customs clearance or food/pharma-grade entry permits. |
Production Scales & Quality Assurance Capabilities
- Multi-Ton Industrial Capacity: Our plant runs a fully automated, digitally managed folic acid production workshop with an annualized capacity of several hundred tons. Powered by a DCS automation system, we eliminate human operational errors, making us fully equipped to handle large blanket orders from multinational pharmaceutical groups and feed conglomerates.
- CNAS-Standard Quality Control Lab: Operating independently from the production division, our QC laboratory features state-of-the-art analytical instrumentation, including Agilent High-Performance Liquid Chromatography (HPLC-DAD), UV-Vis Spectrophotometers, and Atomic Absorption Spectrometers (AAS). Full-spectrum retention samples are kept for every outbound lot.
- Uninterrupted Environmental Compliance: We have invested millions in high-standard Regenerative Thermal Oxidizers (RTO) for gas emissions and advanced wastewater treatment plants. Operating with full environmental validation, our plant maintains uninterrupted production throughout regulatory inspection seasons.
Related References:
Our Promise: Technical Post-Sale Commitments
- Lot Alignment: Production batches precisely mirror the pre-shipment evaluation samples approved by your quality team.
- Formulation Advisory: If you encounter compressibility, binding, or stability issues when blending folic acid with Vitamin B12, iron, or other excipients, our chemical application engineers will provide remote formulation troubleshooting within 48 hours.
- Traceable Discrepancy Protocol: We back our production with an absolute quality guarantee. If independent third-party laboratory re-testing reveals any parameters outside of agreed COA limits, we execute an immediate return-or-replace policy.
