Esmolol Hydrochloride CAS 81161-17-3

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Esmolol hydrochloride
81161-17-3

Name: Esmolol Hydrochloride

Cas: 81161-17-3

Purity: 99%min

MOQ: 1KG

Directory Guidance on Esmolol Hydrochloride

Chemical Structure

Esmolol hydrochloride

Basic Info:

CAS No:81161-17-3
Formula:C16H26ClNO4
EINECS:636-017-0
Stock AvailabilityIn stock
Brand NameLook chemical
OriginChina

Product Introduction:

Esmolol hydrochloride is a chemical with the chemical name (±)-3-{4-[2-hydroxy-3-(1-methylethylamino)propoxy]phenyl}propionic acid methyl ester salt acid salt. It is an ultra-short-acting selective β1-receptor blocker of the aryloxypropylamine class.

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Nature and Specifications:

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Product Usage:

Esmolol hydrochloride inhibits β1 receptors mainly by competing for catecholamine binding sites, and has the effects of slowing resting and exercise heart rate, lowering blood pressure and myocardial oxygen consumption. At the same time, it has the characteristics of fast onset, high bioavailability, short half-life, exact curative effect and low side effects.

At present, esmolol hydrochloride is mainly used for the treatment of supraventricular arrhythmia and acute myocardial ischemia, and it also has obvious curative effect on acute myocardial infarction, unstable angina pectoris and postoperative hypertension.

Related References:

  1. Adamson, P.C., Rhodes, L.A., Saul, J.P. et al. The Pharmacokinetics of Esmolol in Pediatric Subjects with Supraventricular Arrhythmias. Pediatr Cardiol 27, 420–427 (2006).
  2. Muller MD, Ahmad TA, Vargas Pelaez AF, Proctor DN, Bonavia AS, Luck JC, Maman SR, Ross AJ, Leuenberger UA, McQuillan PM. Esmolol infusion versus propranolol infusion: effects on heart rate and blood pressure in healthy volunteers. J Appl Physiol (1985). 2017 Mar 1;122(3):511-519. doi: 10.1152/japplphysiol.00940.2016. Epub 2016 Dec 29. PMID: 28035016; PMCID: PMC5401955.
  3. Wikipedia

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