Top Quality Edaravone CAS 89-25-8
Factory Supply Best P-Hydroxybenzaldehyde CAS 123-08-0
17/01/2022
Supply Best P-Hydroxyacetophenone CAS 99-93-4
13/01/2022
Name: Edaravone
Cas: 89-25-8
Purity: 99%min
MOQ: 1KG
Chemical Structure
Basic Info:
| CAS No: | 89-25-8 |
| Formula: | C10H10N2O |
| EINECS: | 201-891-0 |
| Stock Availability | In stock |
| Brand Name | Look chem |
| Origin | China |
Product Introduction:
Edaravone is a nootropic and neuroprotective agent used to aid nervous system recovery after acute cerebral ischemia and subsequent cerebral infarction.
The product was first listed in Japan in April 2001, and is mainly used for the treatment of ischemic stroke in clinical practice.
Edaravone exists in the form of anion and can donate one electron to free radicals to achieve the purpose of scavenging free radicals.
Because its molecular structure contains lipophilic groups, it can easily reach the brain tissue through the blood-brain barrier, and has a protective effect on nerve cell damage caused by cerebral ischemia.
Clinical studies of Edaravone suggest that N-acetylaspartic acid (NAA) is a specific marker of surviving nerve cells, and its content is sharply reduced in the early stage of cerebral infarction.
Edaravone has been shown to attenuate methamphetamine- and 6-OHDA-induced dopaminergic neurotoxicity in the striatum and substantia nigra and did not affect methamphetamine-induced dopamine release or hyperthermia.
It has also been shown to prevent MPTP-mediated dopaminergic neurotoxicity in the substantia nigra, but not in the striatum in particular.
Nature and Specifications:
Product Nature
Specification
Product Nature
- Density: 1,12 g/cm3
- Boiling point: 287 °C 265 mmHg (liters)
- Melting point: 126-128°C (ignition)
- Flash point: 191°C/17mm
- Water solubility: 3 g/L (20 ºC)
- Stability: Stable under normal temperature and pressure.
Specification
| Item | Specification |
| Product Name | Edaravone Powder |
| CAS No. | 89-25-8 |
| Appearance | Yellow to beige crystalline powder |
| Shelf Life | 2 years |
| Packing | 1kg/bag,25kg/bag or as your requirements |
Product Packaging
Previous
Next
Product Usage:
Edaravone is mainly used to synthesize pyrazolone antipyretic analgesics such as dipyrone, antipyrine and aminopyrine.
It is also an intermediate of pyrazolone acid dyes such as acid medium jujube red BN, permanent yellow G and color film dyes, pesticides and other fine chemicals.
Edaravone can be used as a reagent for the determination of cobalt, copper, iron, nickel, silver and vitamin B12.
It can be used as an environmentally friendly reagent and a reagent for ESI/MALDI-MS detection of reducing carbohydrates.
Used in the production of pyrazolone acid dyes such as acid bordeaux BN, acid mordant B, orange GR, weak acid bright yellow G, neutral burgundy D-BN, permanent yellow G, leather spray red GL, orange 2RL, brown 2RL / Active disperse bright yellow 3G, yellow brown M-3GR, etc.
Indications for Edaravone:
Currently, edaravone is mainly used for the treatment of ischemic stroke.
However, its free radical scavenging and antioxidant effects have been confirmed, and various experimental studies have also shown that edaravone has a protective effect on other organ damage.
It is suggested that the role of it is not only limited to the treatment of ischemic stroke, but also plays a role in the treatment of various diseases closely related to oxidative stress.
Japan, as the original research country, is also used in multiple departments in the application of edaravone, such as neurology, brain surgery, cardiology, internal medicine, thoracic surgery, emergency department, surgery, respiratory department, gastroenterology, plastic surgery and pediatrics.
The specific application areas of Edaravone are as follows:
- Neurology: mainly used in cerebral infarction, viral encephalitis, facial neuritis, epilepsy
- Neurosurgery: mainly used for cerebral hemorrhage, head injury, spinal cord injury
- Cardiology: mainly used for myocardial infarction, viral myocarditis
- Emergency department: mainly used for cerebral infarction, cerebral hemorrhage, craniocerebral injury, carbon monoxide poisoning, paraquat organophosphate poisoning, etc.
- Orthopedics: mainly used for orthopedic surgery, femoral head necrosis and spinal cord injury, etc.
In addition, there are diabetic peripheral neuropathy in endocrinology;
ENT, ischemic optic nerve injury;
Protection of lungs during thoracotomy in thoracic surgery;
The protection of multiple organs during anesthesia surgery, and its application in oncology and organ transplantation.
Related References:
- The good effect of edaravone on patients with acute cerebral large vessel occlusion – PMC | 2015 Mar; 55(3): 241–247.
- FDA approves drug to treat ALS – FDA | May 05, 2017.
- Wikipedia
Our Promise:
Achievements
Service
FAQ
Advice on Shipping
Achievements
I’m william, CEO of Look Chemical Co., Ltd. Welcome to visit our company. As China’s top Global Supply Specialist of chemicals, we have always been adhering to the principle of “service first, quality first, mutual benefit”, and we insist on Create value for customers and grow together with customers.
In the past few years , we have provided efficient and satisfactory services to more than 6000 customers and have been widely praised internationally. In the future, we will strive to provide more than 100,000 customers with professional and thoughtful services, and strive to become your first choice for worry-free purchasing chemicals in China , Hope to bring you a good cooperation experience. If you have any questions, please feel free to contact us.
Service
Pre-Sales Service
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
FAQ
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
Advice on Shipping
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
