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D-Mannitol (C6H14O6), also known as Maniton-S, is a hexavalent alcohol widely distributed in animals, plants or plant secretions. It can be extracted from kelp or seaweed, and can also be prepared by catalytic hydrogenation of glucose or sucrose.
D-Mannitol is a white crystalline solid, odorless, with a cool sweet taste. Some fruits and vegetables contain small amounts of D-mannose, including: cranberries, apples, oranges, peaches, cauliflower, green beans.
D-mannitol is an isomer of sorbitol, an important difference between the two is: sorbitol is very hygroscopic, while D-mannitol is completely non-hygroscopic, so it is a useful Dehydrator.
It is also a monosaccharide structurally related to glucose, involved in numerous metabolic processes, especially in the glycosylation of certain proteins, and plays an important role in many tissues and organs.
D-Mannose is listed on the World Health And Wellness Organization Model Listing of Important Medicines, a listing of one of the most crucial medications needed in the necessary healthcare system.
For The Pharmaceutical Industry:
D-Mannitol is a good diuretic in medicine, reducing intracranial pressure, intraocular pressure and treating kidney medicine, dehydrating agent, sugar substitute, and also used as an excipient for tablets and a diluent for solid and liquid.
D-Mannitol Injection, as a hyperosmotic antihypertensive drug, is a commonly used drug in clinical rescue, especially in brain disease rescue.
As an excipient for tablets, D-mannitol has no hygroscopicity, fast drying, good chemical stability, and has the characteristics of refreshing taste and good granulation. It is used in anticancer drugs, antibacterial drugs, antihistamines and vitamins Most tablets.
In addition, D-mannitol is also used in chewable tablets such as hangover medicines and mouth fresheners.
Application in Food:
The item has the least water absorption amongst sugars as well as sugar alcohols, and also has a revitalizing sweetness. It is utilized for the anti-sticking of maltose, eating gum, rice cakes as well as other foods, as well as the anti- sticking powder for general breads. It can also be used as a low-calorie, low-sugar sweetener in foods for diabetics and bodybuilding foods.
Although D-mannitol can be absorbed by the human gastrointestinal tract, it does not accumulate in the body. After being absorbed, a part is metabolized in the body and the other part is excreted in the urine.
Generally used as sweeteners (low calorie, low sweetness), nutritional supplements, quality improvers, cakes, gums and other anti-sticking agents, heat preservation agents, etc.
Used as Reagent:
It is used for the determination of boron in chemical analysis, and it is used as a bacterial culture agent in biological testing. Dibromomannitol can be obtained by reaction with hydrobromic acid.
Verification and determination of boron and germanium, biochemical research, polarographic analysis of boron, metal masking agent, standard for determination of hydroxyl in organic trace analysis, renal function test, haploid breeding. In Microbiology: D-Mannitol is a good medium for certain microorganisms.
Use in Industry:
In industry, it can be used in the plastics industry to make rosin esters and artificial glycerin resins, explosives, detonators (nitrated D-mannitol), etc.
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