Cinnamyl Chloride CAS 21087-29-6
Name: Cinnamyl Chloride
CAS: 21087-29-6
Purity: 99%min
MOQ: 1KG
Chemical Structure
Basic Info:
| CAS No: | 21087-29-6 |
| Name: | Cinnamyl Chloride |
| EINECS: | 220-246-4 |
| Formula: | C9H9Cl |
| Weight: | 152.62 |
| Other Names: | SORBIC ACID SODIUM SALT |
| Type: | Chemical reagents |
| Shelf Life: | 3 years |
| Brand Name: | Look Chem |
| Place of Origin: | Shandong, China |
Product Introduction:
Cinnamyl chloride, additionally referred to as 3-chloro-1-phenyl-1-propene and cinnamic chloride, is a really essential natural compound. Its molecular formula is C ₉ H ₉ Cl, with a molecular weight of roughly 152.62. At space temperature level, it is normally a yellow to brownish liquid with a distinct molecular structure: a benzene ring is linked to a chlorine atom via an acrylic group, developing a steady conjugated system. Speaking of its physical properties, its melting point is -19 ° C, and under a pressure of 12 mmHg, its boiling point can reach 108 ° C. Its thickness is about 1.096 g/mL, and its refractive index is 1.584. This compound exists in several isomers, with the most common being the trans structure.
As a fragrant compound consisting of allyl chloride structure, cinnamyl chloride has high chemical reactivity due to the fact that its chlorine atom is located in the allyl setting, making it specifically prone to alternative reactions. It can liquify in many natural solvents, but its solubility in water is relatively inadequate. From a security point of view, cinnamyl chloride is a hazardous and hazardous chemical that is not just destructive, however likewise has acute toxicity. Whether inhaled or unintentionally ingested, it might trigger severe injury to the human body. Skin get in touch with can also create burns, and eye call can also cause damages. So, this material should be stored in a cool and dry environment at 0-6 ° C and sealed, and direct skin get in touch with should be purely prevented.
Nature and Specifications:
Specification
Specification
| Item | Specification |
| Product Name | Cinnamyl Chloride |
| CAS No. | 21087-29-6 |
| Appearance | Colorless to Light Yellow Liquid |
| Shelf Life | 2 years |
| Packing | 1kg/bag,25kg/bag or as your requirements |
Product Packaging
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Cinnamyl Chloride Uses:
Cinnamyl Chloride is a versatile great chemical intermediate that plays an important duty in numerous areas. In the field of medication, it is mostly made use of for the synthesis of cardio and cerebrovascular medicines (such as Naoyizi, Flunarizine), antifungal medications (Naftifen), and anti-tumor medications (Torimifene); In the spice industry, it is not just a vital seasoning raw material, but additionally a key intermediate for manufacturing various other flavors; In the fields of organic synthesis and fine chemical design,Cinnamyl Chloride can be utilized to prepare photoresist products, natural metal substances, and can additionally take part in the total synthesis of complex all-natural products. It is specifically because of its active allyl chloride framework that it has actually become a vital “foundation” for creating numerous useful particles.
In the pharmaceutical market, Cinnamyl Chloride is a crucial pharmaceutical intermediate that is usually made use of to manufacture cardiovascular and cerebrovascular medications, such as calcium villain medications like Naoyizi (additionally known as Guilizin) and cinnamyl piperazine. In addition, Cinnamyl Chloride can likewise be used to manufacture the antimicrobial medication naltifen and the anti-tumor medication toremifene. Also the commonly made use of calcium antagonist Flunarizine Dihydrochloride can be manufactured making use of cinnamyl chloride. These medications have substantial clinical application worth in the treatment of cardio and cerebrovascular conditions, fungal infections, and lumps.
Cinnamyl Chloride itself is additionally a vital flavor, commonly utilized in the preparation of seasonings in great chemicals and natural synthesis. It can be used as a basic material to synthesize various other flavor substances, such as for the prep work of the spice cinnamic acid ester. Part of the demand for cinnamyl chloride in the international market comes from the synthesis of respiratory APIs. At the same time, it is typically made use of to produce flavorings and significance, enhancing the scent of various products.
In the field of organic synthesis, Cinnamyl Chloride is a key resources for preparing different substances. For example, it reacts with hexamethylgermanium under the catalytic action of Pd ₂ (dba) ∝ to get cinnamyl trimethylgermanium; Under the catalysis of copper compounds, 4-phenyl-3-butene nitrile can be generated by responding with trimethylcyanosilane. The commonly made use of polyvinyl alcohol cinnamate (an adverse photoresist) additionally entails cinnamyl chloride relevant reactions in its preparation procedure. This photoresist undergoes cross-linking responses under ultraviolet light irradiation and is widely utilized in the handling of micro patterns such as integrated circuits, published circuit boards, and metal indicators. In addition, under the action of palladium catalyst, Cinnamyl Chloride can also undergo regioselective responses with aryl and alkene based (I) phosphines, helping in the asymmetric overall synthesis of naturally active marine diterpenes – heliporins C and E.
Related Industry Q&A
Q1: What are the major uses of cinnamyl chloride in the pharmaceutical industry?
A: Mostly utilized as a pharmaceutical intermediate for the synthesis of cardiovascular and cerebrovascular medications (such as Naoyizi and Flunarizine), antifungal medicines (naltifen), and anti-tumor medicines (toremifene).
Q2: What are its applications in the seasoning market?
A: It can be utilized as a seasoning itself, in addition to an intermediate for the synthesis of other flavor substances (such as cinnamate), and is extensively made use of in the manufacturing of flavor representatives and significance.
Q3: What can it be used for in organic synthesis?
A: It can be used to prepare photoresist materials (such as polyvinyl alcohol cinnamate), organic steel substances (such as cinnamyl trimethylgermanium), and can likewise participate in the overall synthesis of intricate all-natural items (such as helium pore proteins).
Q4:Why is its reactivity high?
A: Since its molecule has an allyl chloride structure, with the chlorine atom in the allyl placement, it is prone to alternative responses, making it a vital foundation for creating numerous practical particles.
Q5: What are the major item kinds or requirements?
A: Normally a yellow to brown fluid, it is identified into various purity levels according to its use in industry, with pharmaceutical quality having stricter needs for contamination control.
Q6: What are the unique demands for storage space and transportation?
A: It needs to be stored in an awesome and dry setting at 0-6 ° C and secured, staying clear of straight skin contact as it is corrosive and acute toxic, requiring added interest.
Q7: What should be noted for secure procedure?
A: It is corrosive and annoying. When operating, it is essential to put on safety tools, prevent breathing, and do not let it come into contact with the skin and eyes. It is best to utilize it in a well aerated area.
Related References:
Cinnamyl Chloride Manufacturer & Supplier
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