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Benzil
Benzil

Name: Benzil

CAS: 134-81-6

Purity: 99%min

MOQ: 1KG

Directory Guidance on Benzil

Chemical Structure

134-81-6

Basic Info:

CAS No:134-81-6
Name:Benzil
EINECS:205-157-0
Formula:C14H10O2
Weight:210.23
Other Names:Dibenzoyl; Diphenyl ethanedione
Type:API; Organic raw materials
Shelf Life:3 years
Brand Name:Look Chem
Place of Origin:Shandong, China

Product Introduction:

Yellow prismatic crystals. Soluble in ethanol, ether, chloroform, ethyl acetate, benzene, toluene, and nitrobenzene, but insoluble in water. Relative density 1.23. Melting point 95°C. Boiling point 346-348°C.

The chemical formula is (C6H5CO)2, often abbreviated as (PhCO)2. It is an α-diketone, consisting of ethane-1,2-dione substituted with phenyl groups at the 1- and 2-positions.

Benzil, also known as diphenylethylenedione, is a biaryl compound, particularly biphenyl compounds, which are important building blocks found in a wide range of pharmaceutical compounds, pesticides, and functional materials. The synthesis of these building blocks is crucial for the production of these drugs and materials. They are used as intermediates in organic synthesis, as photocuring agents for pesticides, photosensitive adhesives, and photocurable coatings, as well as pharmaceutical intermediates.

Nature and Specifications:

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Benzil Uses:

  • In dyes
    Benzil and its derivatives are widely used in dyes, organic photovoltaic sensitizers, biomarkers, and fluorescent probes, as well as synthons for the synthesis of heterocyclic compounds with biological and therapeutic applications. In particular, it is often used for free radical curing of polymer networks, where UV radiation decomposition promotes the generation of free radicals within the material, leading to crosslinking. Benzil is commonly used as a photoinitiator in polymer chemistry. Benzil has also been shown to selectively inhibit human carboxylesterase, which is involved in the hydrolysis of carboxylic esters and many clinical drugs.
  • In medicine
    Benzil is used as a drug intermediate and a photosensitizer for UV-curable resins. In polymer chemistry, it is used as a photoinitiator. Furthermore, it is a potent inhibitor of human carboxylesterase. It can react with amines to prepare diketimines. It also participates in the well-known benzoyl-benzilic acid rearrangement reaction. Furthermore, it reacts with 1,3-diphenylacetone to form tetraphenylcyclopentadienone.

Benzil has potential applications in biological metabolism and clinical medicine. Benzil derivatives exhibit free radical scavenging, antibacterial, antihypertensive, antiprotozoal, antiproliferative, and antimitotic activities. Benzil derivatives are widely used in the pharmaceutical industry to synthesize various heterocyclic compounds, such as triazines, quinoxalines, and imidazoles, from 1,2-diketones. Benzil derivatives are also used as nanocatalysts for imidazole derivatives. Recently, benzil derivatives have been reported to be useful as photosensitizers and photoinitiators due to their antitumor activity.

Main Effect:

  • Organic Synthesis Intermediates
    Benzoin is widely utilized in natural synthesis, particularly in the prep work of heterocyclic compounds. For instance, it reacts with compounds such as urea and aniline to produce oxazoles and imidazoles. These substances possess vital pharmacological tasks and are widely researched and created in medicinal chemistry.

  • Polymer and Products Science
    Due to its superb photosensitivity and fluorescence buildings, benzoin is widely made use of in the prep work of photoinitiators. Intoxicated of ultraviolet light, benzoin can launch totally free radical polymerization, which is especially essential in photolithography and polymer product production.
  • Optical Study and Analytical Chemistry
    The fluorescent residential or commercial properties of benzoyl make it a frequently used reagent in optical experiments and materials testing. For example, it can be utilized to find the absorption or exhaust of light at specific wavelengths. In addition, benzoyl is used in the development of novel fluorescent probes and sensing units.
  • Medical Research study
    Benzoyl derivatives also possess particular organic activities and show appealing application prospects, particularly in the development of anti-bacterial and anti-tumor drugs. Through molecular alteration, benzoyl can be designed into a series of medicine lead substances with details capabilities.

Related References:

  1. DR. SABA KAUSER J. SHAIKH . Benzils: A Review on their Synthesis[J]. Asian Journal of Organic Chemistry.
  2. Wikipedia

Benzil Manufacturer & Supplier

As an experienced Benzil manufacturer and supplier, Look Chemical is committed to producing and selling high quality products.

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Product Data:

1. Certificate Of Analysis (COA)

2. Material Safety Data Sheet (MSDS)

3. Route of synthesis (ROS)

4. Method of Aanlysis (MOA)

5. Nuclear Magnetic Resonance (NMR)

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