Alpha Lipoic Acid, also known as lipoic acid or caprylic acid, is a powerful antioxidant that sits at the center of the antioxidant network and is often referred to as a “broad antioxidant”.
The best Alpha Lipoic Acid has one chiral center and therefore has both R and S configurations.
Natural Alpha Lipoic Acid is a white crystal with only R configuration, and only R configuration lipoic acid can be covalently conjugated to lysine residues through amide bonds to play the function of coenzyme.
The synthetic Alpha Lipoic Acid is a mixture of the R configuration and the S configuration in equal proportions. It is a pale yellow powdery substance that is easily soluble in lipid solvents.
Low solubility in water, about 1 g/L (20°C), soluble in 10% NaOH solution, soluble in aliphatic solvents, easily soluble in methanol, ethanol, chloroform and ether.
DL-lipoic acid is a unique anti-radical substance, a vitamin-like substance produced in the body that is essential for aerobic metabolism.
In addition to helping cells convert glucose into energy, Alpha Lipoic Acid also detoxifies the body, resists skin inflammation and stabilizes blood sugar.
Currently, α-lipoic acid is part of a multivitamin formulation and is a common ingredient in anti-aging supplements and even pet food.
Alpha Lipoic Acid can be added to vitamin drugs to stimulate fat metabolism.
It is used for the treatment of acute and chronic hepatitis, liver cirrhosis, hepatic coma, fatty liver, diabetes and other diseases and the curative effect and health care, so it is often used in health care and medical supplies.
Alpha Lipoic Acid can be used as an antioxidant and also as a coenzyme such as pyruvate dehydrogenase and glycine decarboxylase, exogenous lipoic acid is lowered by two or even more enzymes in the cell.
This decreased type impacts the cellular procedure of scavenging totally free radicals, enhances glutathione synthesis, controls transcription variable activity, as well as decreases phagocytosis of myelin by macrophages.
Alpha lipoic acid is referred to as a “global antioxidant” since it is soluble in water and also fat, and also can pass through tissues such as the nerve system as well as the heart, which are mainly composed of fat and water, so it can protect them from free radical damage.
Unlike other specialized antioxidants generated in the body, DL-lipoic acid is neither purely fat-soluble nor water-soluble, which permits it to enhance the task of other anti-oxidants in the body and also is a widely available alternative when antioxidants are deficient.
The item likewise protects nerve cells in individuals with diabetes mellitus as well as helps deal with outer layer neuropathy.
DL-lipoic acid is an acyl provider that exists in pyruvate dehydrogenase and also a-ketoglutarate dehydrogenase, as well as is very closely pertaining to sugar metabolism.
DL-lipoic acid is extensively dispersed in nature, especially bountiful in liver and also yeast.
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