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Products Description
Name: 5-aminolevulinic acid
Cas: 106-60-5
Purity: 99%min
MOQ: 1KG
Basic Info:
CAS No.: | 106-60-5 |
Formula: | C5H9NO3 |
State: | White crystalline powder |
Stock Availability | Stock Availability |
Brand Name | Look chem |
Origin | China |
Product Introduction:
“5-Aminolevulinic acid” (5-ALA) is an organic compound containing oxygen and nitrogen. It is the common precursor for the biosynthesis of all porphyrin compounds. It is a species widely found in bacteria, fungi, animals and plants. The non-protein amino acids in life are naturally present in plants, essential for plant life activities, and metabolically active physiologically active substances.
There are no toxic and side effects, easy to degrade and no residue. In agricultural production, it can be used as strong seedling agent, yield increasing agent, color enhancing agent, greening agent, defoliating agent, herbicide, insecticide, and it can also be used as anticancer drug photochemotherapy in clinical medicine. The effect is peculiar when the agent is used.
5-aminolevulinic acid is the prefix compound of tetrahydropyrrole (tetrahydropyrrole is a substance that constitutes heme, cytochrome, and vitamin B12). It is an essential substance for organisms to synthesize chlorophyll, heme, and vitamin B12.
It is often used in agriculture to increase light and efficiency, promote color change, and so on.
Chemical and physical properties of 5-aminolevulinic acid:
Density: 1.2±0.1 g/cm3
Boiling point: 298.4±20.0 °C at 760 mmHg
Molecular formula: C5H9NO3
Molecular weight: 131.130
Flash point: 134.3±21.8 °C
Exact quality: 131.058243
PSA: 80.39000
LogP: -0.93
Appearance: white crystalline powder
Vapor pressure: 0.0±1.3 mmHg at 25°C
Refractive index: 1.482
Mechanism of action:
“5-Aminolevulinic acid” (5-ALA), as a multifunctional plant growth regulator, is involved in photosynthesis, respiration and transpiration of plants. Not only is it directly involved in the synthesis of plant chlorophyll, heme and phytosensitizer, but it can also significantly promote the transportation of biological information in the body (it can be transported in the plant or generate a certain signal to be transmitted to other parts of the plant), fully activate plant genes, and mobilize excellent plant traits Significant performance.
Increase the chlorophyll content, enhance the electron transfer activity of the donor side and the acceptor side of the photosystem II reaction center, and improve the efficiency of photosynthetic energy conversion. Increase the stomata opening of the blade and improve the carbon dioxide fixation ability. Promote transpiration, increase the absorption and utilization and transformation efficiency of soil mineral elements by crop roots.
Therefore, 5-ALA can promote seed germination, shorten the production cycle, reduce the amount of fertilizer, improve fertilizer utilization efficiency, cultivate strong seedlings, promote early maturity of fruits, increase sugar and color, improve crop resistance and growth robustness, significantly increase production, improve quality, etc. Kind of function.
References: ChEBI、Sciencedirect
Specification:
| Item | Specification |
| Product Name | 5-aminolevulinic acid |
| CAS No. | 106-60-5 |
| Appearance | White crystalline powder |
| Content | 99% min |
| Shelf Life | 2 years |
| Packing | 1kg/bag,25kg/bag or as your requirements |
Medical field application:
- Medically, 5-aminolevulinic acid, as a new type of photodynamic drug, is used not only for the treatment of local or systemic skin cancer, but also for the diagnosis of bladder cancer, gastrointestinal cancer, lung cancer, etc.
- 5-ALA is a second-generation photosensitizer and a photodynamic therapy (PDT) drug. Photodynamic therapy refers to a new treatment method that only produces a therapeutic effect under the irradiation of a certain wavelength of light after the drug is given. It is the fourth increasingly mature treatment after surgery, radiotherapy, and drug therapy.
- As a photosensitizer, 5-ALA has a wide range of applications and can be used for acne, actinic keratosis, various skin diseases, bladder cancer, condyloma acuminatum, upper gastrointestinal cancer, rectal cancer, breast cancer, port wine stains, and senile Treatment of diseases such as macular degeneration and rheumatoid arthritis. For example, the cure rate for basal cell carcinoma is 91%, the cure rate for acne is more than 95%, and the treatment of bladder cancer and psoriasis, which is considered a chronic disease, has achieved satisfactory results.
- 5-aminolevulinic acid is also an important organic synthesis intermediate. Because of its wide-ranging, safe effect and natural pollution-free, it has attracted the attention of domestic and foreign scholars and industry, and has broad application prospects and market development prospects.
Agricultural applications:
As a new type of photoactivating pesticide with high environmental compatibility and selectivity, 5-ALA is widely used in the agricultural field.
- Plant growth regulator
Recent studies have shown that 5-Aminolevulinic acid has the following effects: regulation of chlorophyll synthesis; improved stability of chlorophyll and photoharvesting system II; improved photosynthetic efficiency and accelerated photosynthesis; plants Promotion of tissue differentiation, inhibition of breathing in the dark, enlargement of pores, etc.
Basic physiological activity. Therefore, it is not only an intermediate product of biological metabolism, but also involved in the regulatory process of plant growth and development, has the same physiological activity as plant hormones, and as a plant growth regulator in agricultural production. It can be used. - Green herbicide
The herbicides produced by 5-Aminolevulinic acid can kill weeds in dicotyledonous plants, but are harmless to crops such as grains, wheat and barley, which are mostly monocotyledonous plants, and have a selective herbicide effect.
There are two principles of operation. The first is that it inhibits GluTR gene expression and interferes with 5-ALA synthesis, resulting in the ultimate death of the plant due to a 5-ALA deficiency. The use of such herbicides does not adversely affect the human body, as 5-ALA synthesis in mammals does not go through the C5 pathway. Second, it can relax the regulatory mechanism of 5-ALA synthesis and promote large-scale synthesis of 5-Aminolevulinic acid.
For example, asifluorferamethyl inhibits plant heme synthesis, resulting in the accumulation of large amounts of 5-ALA and porphyrin compounds. Induces peroxidation under quantity and light. However, due to the high market price of 5-ALA and the high quality concentration required for use as a herbicide, it is costly and difficult to apply directly for some time. - Insecticide
It can cause biochemical metabolic imbalances in various pests such as houseflies and cockroaches, causing them to cramp and even die. There is also research on the effects of porphyrin pesticides containing 5-Aminolevulinic acid as the main component of Chinese houseflies. In Jinyuan District, Housefly, all men died in the treatment group within 7 days, and about half of the men died in the control group. There was no significant difference in the number of women with low concentrations.
The principle is as follows. When activated by 5-ALA, reactive oxygen species are produced, which can turn sunlight into radiation pesticides during photosynthesis in plants and cause chemical synthesis of pests. This study shows that it is a pollution-free natural substance, biodegradable and does not develop resistance to pesticides to pests. A new type of green pesticide can be developed.
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Shipping:
1. ≤50kg, Express delivery recommended, usually called as DDU service;
2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;
4. For high value products, please select air shipping and express delivery for safe.
Packaging and shipping
