2-Chloro-3-Nitrobenzoic Acid CAS 3970-35-2
2-Chloro-3-Nitrobenzoic Acid CAS 3970-35-2 | supplier
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Min: 10 Gram
Delivery: 7 Days
Transporta: Ocean, Land,Air, DHL，TNT
Port: Shanghai Port, Qingdao Port
Name: 2-Chloro-3-Nitrobenzoic Acid
CAS: 3970-35-2
Purity: 99%min
MOQ: 1KG
Directory Guidance on 2-Chloro-3-Nitrobenzoic Acid
Chemical Structure
Basic Info:
| CAS No: | 3970-35-2 |
| Name: | 2-Chloro-3-Nitrobenzoic Acid |
| EINECS: | 223-590-3 |
| Formula: | C7H4ClNO4 |
| Weight: | 201.56 |
| Other Names: | 2-Chloro-3-nitrobenzoic acid,98% |
| Type: | Chemical reagents |
| Shelf Life: | 3 years |
| Brand Name: | Look Chem |
| Place of Origin: | Shandong, China |
Product Introduction:
A colleague of mine who runs a process chemistry group once described 2-Chloro-3-Nitrobenzoic Acid as “the awkward one in the benzoic acid family” — and he wasn’t wrong. CAS 3970-35-2. The ortho relationship between the chloro and nitro substituents on the ring creates genuine electronic complexity. The nitro group at position 3 is electron-withdrawing, and the chloro at position 2 does dual duty: it’s a leaving group candidate in nucleophilic aromatic substitution but it also distorts the ring electronics enough to redirect where subsequent reactions prefer to occur.
I’ve seen procurement specs for this come in three flavors. The research-scale guys want small quantities, high purity, fast delivery, and they’ll pay a premium for it. Process development teams want 98%+ with tight impurity specs and a full COA showing actual data — not just “complies with specification” checkboxes. Production groups want reliable supply, price stability, and the ability to scale up without requalifying. If you’re sourcing this for process development, the impurity profile matters more than the headline purity number. Ask for the GC or HPLC trace, not just the summary table.
The compound melts around 155-158°C and is soluble in common polar organic solvents — DMF, DMSO, acetone — but has limited water solubility. That solubility profile is why it works well in certain coupling reactions where you need a homogeneous reaction mixture. It handles elevated temperatures reasonably well, but if you’re using it in acidic conditions at high temp, watch the nitro group — it can be selective about what reactions it participates in.
One thing I’d flag for anyone setting up a handling protocol: the nitro group on an aromatic ring combined with organic residue is worth taking seriously in waste management. Standard lab safety practices apply, but make sure your waste disposal contractor knows what they’re collecting. Don’t assume routine organic waste handling covers energetic materials.
Nature and Specifications:
Specification
Specification
| Item | Specification |
| Product Name | 2-Chloro-3-Nitrobenzoic Acid |
| CAS No. | 3970-35-2 |
| Appearance | Powder |
| Shelf Life | 2 years |
| Packing | 1kg/bag,25kg/bag or as your requirements |
Product Packaging
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2-Chloro-3-Nitrobenzoic Acid Uses:
The main draw in pharmaceutical synthesis is its role as a precursor for building substituted heterocycles — benzimidazoles, benzoxazoles, quinolones. The chloro leaving group gets displaced in the right conditions, and the nitro can be reduced to an amine that then participates in ring closure. That two-step sequence — SNAr then reductive amination — appears in quite a few drug synthesis routes, especially for kinase inhibitor programs where substituted aromatic cores are everywhere.
In agrochemical work,2-Chloro-3-Nitrobenzoic Acid compound shows up as a building block for certain herbicide and fungicide candidates. The nitrobenzoic acid scaffold is a recurring motif in crop protection chemistry. If you’re doing contract synthesis for an agrochemical program, make sure you’re sourcing from a supplier who can provide the regulatory documentation your client will eventually need — SDS in the right format, COA with specific impurity data, origin documentation.
There’s also a smaller volume use in specialty dye synthesis, where the aromatic ring with its mix of electron-donating and withdrawing substituents contributes to chromophore design. Not the primary market, but worth knowing if you’re evaluating which grades to stock.
Related Industry Q&A
Q1:What purity grade do I actually need for pharmaceutical intermediate work?
For early-stage synthesis — route scouting, milligram-scale method development — 97-98% is usually fine. When you get to late development or scale-up, the spec should tighten to 99%+ with specific limits on individual named impurities, not just “total impurities.” The reason: some impurities in starting materials carry through the synthesis and become problematic in the final API. The earlier you establish tight starting material specs, the fewer surprises you’ll hit at scale.
Q2:How stable is 2-Chloro-3-nitrobenzoic acid during long-term storage?
Properly stored material — sealed container, cool and dry, no UV exposure — holds specification for 24 months or more. The main degradation mode is moisture uptake that eventually affects the physical form rather than chemical decomposition. Reseal containers promptly after use, and if you’re storing large quantities, use an indicator card in the storage area to track humidity levels.
Q3:Can I specify customized impurity limits beyond your standard grade?
Yes, for orders above 25 kg we typically can accommodate custom specifications within our production capability. The lead time and any price impact depend on how far the custom spec deviates from our standard product. Tell us what you need and we’ll assess feasibility — we’d rather have that conversation upfront than have you qualify our standard grade and then find it doesn’t meet your downstream requirements.
Q4:What documentation do you provide for this compound?
Standard package includes: CoA (actual values, not just spec compliance), SDS (GHS format), TDS. For pharmaceutical applications we can support DMF filings with additional manufacturing documentation. For regulated markets we can provide country-of-origin documentation and, for larger programs, facility audit support.
Related References:
2-Chloro-3-Nitrobenzoic Acid Manufacturer & Supplier
As an experienced producer and supplier of 2-Chloro-3-Nitrobenzoic Acid, Look Chemical is committed to producing and selling high-quality products.
We cooperate and trade with over 6000 factories worldwide, and our high-quality products and services have earned us a high reputation internationally.
As a supplier of 2-Chloro-3-Nitrobenzoic Acid, Look Chemical provides supply chain solutions to partners and customers in various industries. We offer highly competitive prices and high-quality products.
If you have a demand for this product, please contact our sales staff and we will provide you with a solution as soon as possible.
Our Promise:
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Achievements
I’m william, CEO of Look Chemical Co, Ltd. Welcome to visit our company. As China’s top Global Supply Specialist of chemicals, we have always been adhering to the principle of “service first, quality first, mutual benefit”, and we insist on Create value for customers and grow together with customers.
In the past few years , we have provided efficient and satisfactory services to more than 6000 customers and have been widely praised internationally. In the future, we will strive to provide more than 100,000 customers with professional and thoughtful services, and strive to become your first choice for worry-free purchasing chemicals in China , Hope to bring you a good cooperation experience. If you have any questions, please feel free to contact us.
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Pre-Sales Service
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* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
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*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
FAQ
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
Advice on Shipping
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Company Info
Look chemical company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
Product Data:
1. Certificate Of Analysis (COA)
2. Material Safety Data Sheet (MSDS)
3. Route of synthesis (ROS)
4. Method of Aanlysis (MOA)
5. Nuclear Magnetic Resonance (NMR)
6. Packing pictures and loading video before loading
7. Free Sample
8. Factory audit
