1,3-Diaminopropane CAS 109-76-2

1,3-Propylenediamine is a low-level aliphatic diamine with active chemical properties. It can be widely used in medicine, pesticides, dyes, petrochemicals, semiconductor manufacturing and polymer industries.

• Epoxy curing agent
  In addition to being used directly as an epoxy resin curing agent, 1,3-propylenediamine can also be made into a latent curing agent through chemical modification. The so-called latent curing agent is a curing agent that has a certain storage stability at room temperature after being combined with epoxy resin, and can quickly crosslink and cure epoxy resin under conditions such as heating, light, moisture or pressure.
• Used in oil additives
  Oil additives refer to certain chemical substances that can significantly improve the original properties of oil products or give oil products certain new qualities when added to oil products. Propylene diamine has good oil solubility compared to ethylenediamine. Early oil passivators were prepared using ethylenediamine. Due to the crystallinity of ethylenediamine, propylenediamine (1,2-propylenediamine and 1,3-propylenediamine) is currently used as a passivator raw material in countries around the world.
• Used in mineral processing industry
  Dodecylamine is a commonly used collector in reverse flotation process, but its effect is not very obvious in bauxite reverse flotation, and its ability to collect aluminum silicate minerals is not strong. N-dodecyl-1,3-propylenediamine is a cationic surfactant. It is mainly used for the separation of hematite from quartz and hematite from common pyroxene in flotation. It is also used for the separation of quartz from feldspar and the separation of barite from fluorite.
• Used for the synthesis of Schiff bases and their metal complexes
  1,3-propylenediamine can be regarded as a compound corresponding to the replacement of two hydrogen atoms in the molecule by two amino groups. It can generate Schiff bases with carbonyl compounds. At the same time, because the molecule contains two highly electronegative nitrogen atoms, 1,3-propylenediamine exhibits strong coordination ability and can form stable complexes with almost all metal elements.

• Used as pharmaceutical synthesis intermediates
  Synthesis of Amifostine
  Amifostine is a broad-spectrum cell protectant recognized by international authoritative organizations. It was developed by the American Bioscience Corporation of Texas and produced by Alza Pharmaceuticals. It was approved by the US FDA for marketing in the United States in 1996. It is usually used as a normal cell protector during radiotherapy and to prevent and reduce the cumulative nephrotoxicity, neurotoxicity and damage to the hematopoietic system caused by multiple doses of cisplatin chemotherapy for advanced ovarian cancer or non-small cell lung cancer and cyclophosphamide chemotherapy for advanced ovarian cancer. Amifostine is mainly made from 1,3-propylenediamine through condensation, bromination and salt formation.

  Synthesis of Methimidine Propylene Diamine
  Methimidine Propylene Diamine-ETDA (MPE for short) is a biological genetic material DNA cutting agent, which has extremely wide applications in the determination of drug action sites, biochemical research and cutting reagent standards, especially in the field of life sciences. Methimidine Propylene Diamine is an essential compound for the synthesis of MPE, which is mainly made from 2-aminobiphenyl as the starting material through nitration, amidation, cyclization, methylation, reduction and amidation reactions.