Good Price 1-Phenyl-2-Nitropropen for Vat Dyes CAS 129-56-6

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1-Phenyl-2-Nitropropen
129-56-6

Products Description

Name: 1-Phenyl-2-Nitropropen

Cas: 129-56-6

Purity: 99%min

MOQ: 1KG

Basic Info:

CAS No:

129-56-6

Formula:

C14H8N2O

EINECS:

204-955-6

Stock Availability

In stock

Brand Name

Look chem

Origin

China

Product Introduction:

1-Phenyl-2-Nitropropen is a compound, a derivative of anthrone. 1,9-Pyrazoloanthrone is used as an inhibitor of c-Jun N-terminal kinase (JNK) in biochemical research.

Derivatives of 1-Phenyl-2-Nitropropen have various biological activities. For example, 5-(aminoalkyl)amino derivatives have been studied as anticancer agents.

Product Nature:

  • Melting point: 281~282℃
  • Boiling point: 361.16°C(roughestimate)
  • Density: 1.1702(roughestimate)
  • Refractive index: 1.591Chemicalbook0(estimate)
  • Solubility: H2O:insoluble
  • Acidity coefficient (pKa): 11.75±0.20(Predicted)

Specification:

ItemSpecification
Product Name1-Phenyl-2-Nitropropen
CAS No.129-56-6
Appearance Yellow or dark yellow powder
Content99% min
Shelf Life2 years
Packing1kg/bag,25kg/bag or as your requirements

Product function:

  • 1-Phenyl-2-Nitropropen can be used as a dye intermediate, mainly for the production of dyes such as vat ash M.
  • Pyrazoxanthone can obtain useful derivatives through simple substitution, and produce a variety of vat dyes.
  • Derivatives of 1-Phenyl-2-nitropropene have a variety of biological activities. For example, 5- (aminoalkyl) amino derivatives have been studied as anti-cancer agents.

In vitro studies on 1-Phenyl-2-Nitropropen:

SP600125 is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK) with an IC50 of 40 nM to 90 nM. SP600125 acts on Jurkat T cells and inhibits c-Jun phosphorylation at IC50s in the 5 μM to 10 μM range.

SP600125 acts on CD4. However, later studies have shown that SP600125 also inhibits the aroma hydrocarbon receptor (AhR) Mps1 and a series of other serine / threonine kinases such as Aurora kinase A, FLT3, MELK, and TRKA.

20 μMSP600125 acts on MIN6 in mouse beta cells to induce phosphorylation of p38MAPK and activation of its downstream CREB-dependent promoter.

20 μMSP600125 acts on HCT116 cells to stop G2 mitosis and induce nuclear replication.

References:

  1. Showalter HD, Johnson JL, Werbel LM, Leopold WR, Jackson RC, Elslager EF (1984). “5-[(Aminoalkyl)amino]-substituted anthra[1,9-cd]pyrazol-6(2H)-ones as novel anticancer agents. Synthesis and biological evaluation”. J. Med. Chem27 (3): 253–5. doi:10.1021/jm00369a002. PMID 6699870.
  2. Wikipedia

Service:

Pre-Sales Service

* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.

* The sample supports testing and inspection.

* Each batch of products will be tested to ensure that its quality meets user needs.

*Packaging can also be made according to customer requirements.

*Any inquiries will be answered by our relevant personnel within 24 hours.

*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.

 

After-Sales Service

*We will monitor the logistics information in real time and will share the information with you.

* You can consult us at any time if you have any questions about the product, and we will answer you in time.

*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.

Shipping:

1. ≤50kg, we recommend express delivery, usually called DDU service;

2. ≤500kg, air transportation is generally recommended, usually called FOB, CFR or CIF service;

3.>500kg, sea freight is generally recommended, usually called FOB, CFR or CIF service;

4. For high-value products, please choose air and express to ensure the safety of the products.

FAQ

Do you accept sample order?

We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.

How to confirm whether the product quality meets our needs before placing an order?

You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.

What’s your MOQ?

Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Learn more about us

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1-Phenyl-2-Nitropropen
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