Chlorphenesin (Preservative) in Skin Care | Safety & Uses

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Chlorphenesin (Preservative) in Skin Care | Safety & Uses

When it comes to preservatives, some people will resist, thinking that chemically synthesized things are not good anyway. However, most of the preservatives are synthetic, and it will cause some harm to the human body if it exceeds the standard range of use.

This is because these antibacterial substances, such as various essential oils and certain alcohols, are not regarded as either in my country’s cosmetic safety technical specifications or in the annex to the EU Cosmetics Directive “List of Preservatives that Can Be Contained in Cosmetics” preservative.

Chlorphenesin Definition (General Description)

Chlorphenesin is a broad-spectrum antiseptic and antibacterial agent. It has killing effect on most Gram-positive and negative bacteria and fungi. Widely used in cosmetics, compatible with most preservatives (including potassium sorbate, sodium benzoate, methylisothiazolinone).

Non-irritating and low toxicity, it is an important antifungal drug allowed by EU and Chinese regulations.

It has good chemical stability and will not be inactivated under storage conditions.


Chlorphenesin for Sale
Chlorphenesin Powder

Chlorphenesin is a white to off-white crystalline powder, usually with a weak characteristic odor. The melting point is 77.0-80.5°C. Slightly soluble in water (about 0.5%). The solubility in 95% ethanol is 5%. Soluble in ethers. Slightly soluble in fixed oil, insoluble in white mineral oil.

Function and Effect in Cosmetics

  1. Compared with other preservatives, chlorphenesin is used in a lower concentration in cosmetics. The maximum usage amount of chlorphenesin in the “Cosmetic Regulations” is 0.3%, and 0.01% can play a preservative effect. – Click to learn about “Cosmetic Regulations
  2. Does not contain any free or bound formaldehyde, and has good local skin or mucous membrane tolerance.
  3. It will not denature protein and increase fat oxidation. (Phenolic preservatives often cause this effect)
  4. Low toxicity and certain anti-dermatophytic effect.
  5. Chlorphenesin is used as a cosmetic fungicide in the “International Dictionary and Handbook of Cosmetic Raw Materials”, which can effectively resist Gram-positive and negative bacteria.
  6. Compatible with most preservatives, more versatile. It can be compounded with phenoxyethanol, polyols, potassium sorbate, sodium benzoate, methylisothiazolinone, etc.

Is chlorophenesin safe for skin?

Chlorphenesin is a safe and effective preservative added in limited quantities in cosmetics.

It does not contain formaldehyde, nor is it a formaldehyde releaser. It will not denature proteins. It is an effective and low-toxic antibacterial and antifungal agent, which can effectively prevent the product from color and unpleasant odor caused by microbial growth.

Appropriate concentrations of chlorphenesin are not irritating to healthy skin.


Microbial control performance: Chlorphenesin can provide improved broad-spectrum antibacterial activity. It has the ability to inhibit and kill G+, G-, Aspergillus niger, Penicillium pinophilum, Candida albicans and Saccharomyces cerevisiae.

Used in combination with other preservatives, the antiseptic effect is enhanced. At the same time, it is more effective against fungi, for example, it has a good antibacterial and bactericidal effect on microorganisms such as Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and mold.

Chlorphenesin Raw Material Manufacturer & Supplier

Look Chemical is a great place to buy chlorphenesin powder. We supply chlorphenesin with high quality and are occupying the market with competitive price. At the same time we have professional customer service and first-class production lines and equipment.

As an experienced chlorphenesin manufacturer and supplier. Look Chemical manufactures and supplies high quality products for customers all over the world.

Offer you products at the best price. There are no middlemen to make the difference, saving you production costs while getting high-quality products.

Over the years, we have actually worked with over 6,000 clients worldwide. With high-quality products and excellent service, our company has won many praises.

If you need chlorphenesin or its related products, please contact us. Our service team is at your service 24 hours a day.

More Info

It is almost inevitable to add preservatives to cosmetics. We should know that we live in an environment with bacteria. Most cosmetics contain water and nutrients, and the water activity and pH range are suitable for the growth of microorganisms. Preservatives can effectively inhibit the growth of microorganisms. If preservatives are not added, the product is easy to breed microorganisms, causing the product to breed bacteria, mold and deteriorate, and then bring harm to skin health.

Even vacuum-packaged products are isolated from bacteria in the air, and the possibility of contamination or oxidation is greatly reduced. But as long as skin care products contain active ingredients or ingredients that interact easily, preservatives are generally added. Otherwise, microbes will “multiply offspring” in the product and on the face, and the scene is simply unsightly!

Among many preservatives, chlorpheniramine is one of the preservatives that can inhibit the growth of bacteria at low concentrations. The maximum dosage of chlorpheniramine in the “Cosmetic Regulations” is 0.3%, and 0.01% can play a preservative effect. It is an effective low-toxic antibacterial and antifungal agent, which can effectively prevent the color and odor of the product caused by the growth of microorganisms.

During the preparation of chlorpheniramine, there may be raw material residues reacting with chlorophenols, producing pungent odorous gases, and giving people an unpleasant sense of smell. At the same time, it also has considerable side effects, causing harm to the human body. In order to solve this residual problem, Zhuanglai Company has finally developed an odorless chlorpheniramine production process after many experiments and researches, which completely solved the toxic and side effects caused by chlorophenol residues.

In fact, the skin care products of regular brands are added in accordance with national standards. Maybe you don’t know that Chinese cosmetics specifications are often stricter than foreign ones. Preservatives can be added. As long as you use regular brand products, you don’t have to worry about the harm of preservatives. It can really be an ally.